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auromomycin

Known as: aur-chromophore, macromomycin chromophore 
National Institutes of Health

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2 relations

Broader (2)

Antibiotics, AntineoplasticPeptides

Papers overview

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2012
2012
A high angular and spectral resolution view into the hidden companion of ε Aurigae
The enigmatic binary, e Aur, is yielding its parameters as a result of new methods applied to the recent eclipse, including… 
1989
1989
Crystal structure analysis of auromomycin apoprotein (macromomycin) shows importance of protein side chains to chromophore binding selectivity.
The crystal structure of macromomycin, the apoprotein of the antitumor antibiotic auromomycin, has been determined and refined at… 
1983
1983
Evidence for involvement of a free radical in DNA-cleaving reaction by macromomycin and auromomycin.
The DNA-cleaving activity of auromomycin (AUR) was prevented by the free radical scavengers alpha-tocopherol and isopropanol… 
1982
1982
Studies on the reconstitution of macromomycin a d auromomycin from the chromophore and protein moieties.
The chromophores extracted from macromomycin (MCR) and auromomycin (AUR) with methanol had identical ultraviolet absorption… 
Highly Cited
1980
Highly Cited
1980
Biological activities of non-protein chromophores of antitumor protein antibiotics: auromycin and neocarzinostatin.
1980
1980
Requirement for reducing agents in deoxyribonucleic acid strand scisson by the purified chromophore of auromomycin.
By methanol extraction and high-pressure liquid chromatography a nonprotein chromophore has been obtained from the antitumor… 
Highly Cited
1980
Highly Cited
1980
Stabilization of neocarzinostatin nonprotein chromophore activity by interaction with apoprotein and with HeLa cells.
The methanol-extracted, nonprotein chromophore of the protein antibiotic neocarzinostatin (NCS), which possesses the full in… 
Highly Cited
1979
Highly Cited
1979
Studies on auromomycin.
A new antitumor antibiotic, named auromomycin, was isolated from the culture broth of Streptomyces macromomyceticus, a… 
1979
1979
DNA strand scission in vivo and in vitro by auromomycin.
The mechanism of action of auromomycin, a new tumor-inhibitory antibiotic, was studied in a growing culture of mouse… 
1971
1971
Evidence for a Collapsar in the Binary System ɛ Aur
The mysterious secondary component of ɛ Aur is probably not in a prestellar stage of evolution. It is more likely to be a black… 
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