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aspoxicillin
Known as:
N(4)-methyl-D-asparaginylamoxicillin
A broad-spectrum, semisynthetic penicillin derivative with antibacterial activity. Aspoxicillin binds to and inactivates penicillin-binding proteins…
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (1)
Amoxicillin
Narrower (1)
TA 058
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Total Synthesis of Sarpagine-Related Bioactive Indole Alkaloids.
M. Toufiqur Rahman
,
Jeffrey R. Deschamps
,
Gregory H. Imler
,
James M. Cook
Chemistry
2018
Corpus ID: 46810048
Extension of the asymmetric Pictet-Spengler reaction to bulkier Nb -alkylated tryptophan derivatives resulted in an improved…
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2018
2018
Shorter and Improved Access to the Key Tetracyclic Core of Sarpagine-Macroline-Ajmaline Indole Alkaloids: the Total Synthesis of Alkaloids Macrocarpines A-g, Talcarpine, N(4)-methyl-n(4),21…
Toufiqur Rahman
2018
Corpus ID: 155368728
Part I Chapter 1. A Shorter and Improved Access to the Bicyclo[3.3.1]nonane core of Sarpagine/Macroline/Ajmaline Alkaloids…
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2008
2008
Antimicrobial Susceptibility of Pasteurella multocida Isolated From Cattle and Pigs: Antimicrobial Susceptibility of P. multocida
H. Yoshimura
,
M. Ishimaru
,
Y. S. Endoh
,
Akemi Kojima
2008
Corpus ID: 262103142
1996
1996
Incidence of diarrhea with antibiotics and the increase of clostridia in rabbits.
Y. Hara-Kudo
,
Y. Morishita
,
Y. Nagaoka
,
F. Kasuga
,
S. Kumagai
Journal of Veterinary Medical Science
1996
Corpus ID: 23512272
Rabbits were treated with a single intravenous injection of various antibiotics. More than 40 per cent of the animals showed…
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1994
1994
Aspoxicillin versus piperacillin in severe abdominal infections--a comparative phase III study.
Harry Scheinin
,
T. Havia
,
+4 authors
J. Niinikoski
Journal of Antimicrobial Chemotherapy
1994
Corpus ID: 40070763
We compared aspoxicillin, a new broad-spectrum penicillin derivative, with piperacillin in severe abdominal infection…
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1994
1994
[Studies on aspoxicillin for its transfer to the skin].
M. Kurokawa
,
S. Suzuki
,
+7 authors
M. Naito
The Japanese Journal of Antibiotics
1994
Corpus ID: 21895530
To evaluate the usefulness of aspoxicillin (ASPC) in the field of plastic and reconstructive surgery, we examined its transfer to…
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1990
1990
Activity of sub-minimal inhibitory concentrations of aspoxicillin in prolonging the postantibiotic effect against Staphylococcus aureus.
T. Oshida
,
T. Onta
,
N. Nakanishi
,
T. Matsushita
,
T. Yamaguchi
Journal of Antimicrobial Chemotherapy
1990
Corpus ID: 40886980
Aspoxicillin, a newly developed acylureido-penicillin with a long half-life in mouse serum of 55 min, induced postantibiotic…
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1989
1989
An experimental meningitis with Streptococcus pneumoniae in rats: therapeutic effect of aspoxicillin and its penetration into CSF.
T. Yamaguchi
,
O. Kasuga
,
S. Okuno
,
I. Maezawa
Drugs under experimental and clinical research
1989
Corpus ID: 35788448
An experimental meningitis model was produced in rats with Streptococcus pneumoniae Type III and used to evaluate the therapeutic…
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1988
1988
Pharmacokinetics of aspoxicillin in subjects with normal and impaired renal function.
J. Geyer
,
D. Höffler
,
P. Koeppe
Arzneimittel-Forschung
1988
Corpus ID: 10352584
The pharmacokinetics of aspoxicillin [2S,5R,6R)-6-[(2R)-2-[(2R)-2-amino-3-(methylcarbamoyl)propionam ido]-2- (p-hydroxyphenyl…
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1983
1983
Synthesis and antibacterial activity of asparagine derivatives of aminobenzylpenicillin.
M. Wagatsuma
,
M. Seto
,
T. Miyagishima
,
M. Kawazu
,
T. Yamaguchi
,
S. Ohshima
Journal of antibiotics (Tokyo. )
1983
Corpus ID: 38404059
In order to improve the antibacterial activity of aminobenzylpenicillin, penicillin derivatives having an asparagine moiety in…
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