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ascochlorin

National Institutes of Health

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2 relations

Broader (2)

AlkenesPhenols

Papers overview

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2019
2019
4-O-Methylascochlorin inhibits the prolyl hydroxylation of hypoxia-inducible factor-1α, which is attenuated by ascorbate
4-O-Methylascochlorin (MAC), a methylated derivative of ascochlorin, was previously shown to promote the accumulation of hypoxia… 
2016
2016
Discovery of a new structural class of competitive hDHODH inhibitors with in vitro and in vivo anti-inflammatory, immunosuppressive effects.
2011
2011
Ascochlorin suppresses TGF-β1-induced PAI-1 expression through the inhibition of phospho-EGFR in rat kidney fibroblast cells
Fibrosis is induced by the excessive and abnormal deposition of extracellular matrix (ECM) with various growth factors in tissues… 
2009
2009
LL-Z1272α epoxide, a precursor of ascochlorin produced by a mutant of Ascochyta viciae
A novel metabolite, LL-Z1272α epoxide, structurally related to ascochlorin, was isolated from the cultured mycelium of Ascochyta… 
2009
2009
Relationship between peroxisome proliferator-activated receptor-γ activation and the ameliorative effects of ascochlorin derivatives on type II diabetes
Peroxisome proliferator-activated receptor-γ (PPAR-γ) is a crucial factor in the development of insulin resistance associated… 
2007
2007
Immunosuppressive Activity of 4-O-Methylascochlorin
A major strategy for suppressing immune responses is the elimination of antigen-reactive lymphocytes through apoptosis. 4-O… 
2002
2002
PPARgamma activation and adipocyte differentiation induced by AS-6, a prenyl-phenol antidiabetic antibiotic.
The prenyl-phenol antibiotics ascochlorin-related compounds, are known to reduce serum cholesterol and triglyceride, suppress… 
2001
2001
Pseudodestruxins A and B: new cyclic depsipeptides from the coprophilous fungus Nigrosabulum globosum.
Pseudodestruxins A (1) and B (2), two new cyclic peptides, have been isolated from cultures of the coprophilous fungus… 
1969
1969
Antiviral and antitumor antibiotics. XIV. Effects of ascochlorin and other respiration inhibitors on multiplication of Newcastle disease virus in cultured cells.
Antiviral activity on Newcastle disease virus was examined with some respiration inhibitors including ascochlorin, rotenone… 
Highly Cited
1969
Highly Cited
1969
The molecular structure of ascochlorin.
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