ascochlorin
National Institutes of Health
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Significance Ascofuranone (AF) and ascochlorin (AC) are fungal natural products with similar chemical structures, originally…
Human glioblastomas express higher levels of matrix metalloprotease‐2 (MMP‐2) than low‐grade brain tumors and normal brain…
A natural compound C23H32O4Cl, ascochlorin (ASC) isolated from an incomplete fungus, Ascochyta viciae has been known to have…
Re-identification of the ascofuranone-producing fungus Ascochyta viciae as Acremonium sclerotigenum
The critical initiating event in atherogenesis involves the invasion of monocytes through the endothelial walls of arteries and…
The expression of matrix metalloproteinases (MMPs) has been implicated in the invasion and metastasis of cancer cells. Here we…
Nuclear receptor family proteins are structurally related transcription factors activated by specific lipophilic compounds…
An ascochlorin derivative, AS-6, is a new hypoglycemic agent orally active in both obese hyperinsulineroic and insulin-deficient…
A new antibiotic with hypolipidemic activity, ascofuranone, C23H29C1O5, and related substance, ascofuranol, C23H31C1O5, were…
Antiviral activity on Newcastle disease virus was examined with some respiration inhibitors including ascochlorin, rotenone…