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arvelexin

 
National Institutes of Health

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Papers overview

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Review
2019
Review
2019
Phytochemical and Health-Beneficial Progress of Turnip (Brassica rapa).
Despite the advancement of medical science, diseases are part-and-parcel of human life. Plants have provided humans with… Expand
2014
2014
Anti-inflammatory effects of 7-hydroxyl-1-methylindole-3-acetonitrile, a synthetic arvelexin derivative, on the macrophages through destabilizing mPGES-1 mRNA and suppressing NF-κB activation.
We previously demonstrated that 7-hydroxyl-1-methylindole-3-acetonitrile (7-HMIA), a synthesized analog of arvelexin, showed the… Expand
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2013
2013
Synthesis of indolyl-3-acetonitrile derivatives and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells.
Arvelexin is one of major constituents of Brassica rapa that exerts anti-inflammatory activities. Several indolyl-3-acetonitrile… Expand
2012
2012
Arvelexin inhibits colonic inflammation by suppression of NF-κB activation in dextran sulfate sodium-induced mice and TNF-α-induced colonic epithelial cells.
Recently, we reported the anti-inflammatory effects of arvelexin isolated from Brassica rapa in macrophages. In the present study… Expand
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Highly Cited
2012
Highly Cited
2012
Alkaloids from the root of Isatis indigotica.
Seventeen new alkaloids (1-17) and 14 known analogues have been isolated from an aqueous extract of the root of Isatis indigotica… Expand
2011
2011
Arvelexin from Brassica rapa suppresses NF‐κB‐regulated pro‐inflammatory gene expression by inhibiting activation of IκB kinase
BACKGROUND AND PURPOSE Brassica rapa species constitute one of the major sources of food. In the present study, we investigated… Expand
2011
2011
Interaction of cruciferous phytoanticipins with plant fungal pathogens: indole glucosinolates are not metabolized but the corresponding desulfo-derivatives and nitriles are.
Glucosinolates represent a large group of plant natural products long known for diverse and fascinating physiological functions… Expand
Review
2007
Review
2007
Chemical investigation of phytoalexins and phytoanticipins : isolation, synthesis and antifungal activity
The focus of my research was on the secondary metabolites produced by crucifer plants under stress and their biological activity… Expand
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2005
2005
Chemical study of the blackleg fungus : metabolites, phytotoxins and phytoalexins
New isolates Mayfair 2 and Laird 2 of the blackleg fungus [Phoma lingam, perfect stage Leptosphaeria maculans (Desm.) Ces. et de… Expand
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Highly Cited
2004
Highly Cited
2004
Phytotoxin Production and Phytoalexin Elicitation by the Phytopathogenic Fungus Sclerotinia sclerotiorum
The fungus Sclerotinia sclerotiorum (Lib.) de Bary causes rot disease in a vast range of plant families, including Cruciferae… Expand
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