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arimoclomol

Known as: N-((2R)-2-Hydroxy-3-(1-piperidyl)propoxy)pyridine-3-carboximidoyl chloride, 1-oxide 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

BRX220

Broader (1)

Hydroxylamines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Knockdown of Heat Shock Proteins HSPA6 (Hsp70B’) and HSPA1A (Hsp70-1) Sensitizes Differentiated Human Neuronal Cells to Cellular Stress
Heat shock proteins are involved in cellular repair and protective mechanisms that counter characteristic features of… 
Review
2015
Review
2015
Molecular basis of ALS and FTD: implications for translational studies / Molekularna osnova ALS-a i FTD-a: implikacije za translacijska istraživanja
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative disorders, related by signs of… 
2013
2013
LB0002 Safety and Tolerability of Arimoclomol in Patients with Sporadic Inclusion Body Myositis: A Randomised, Double-Blind, Placebo-Controlled, Phase IIa Proof-of-Concept Trial
Background Sporadic inclusion body myositis (IBM) is the commonest idiopathic inflammatory myopathy occurring in patients over… 
2012
2012
098 Developing new therapeutic strategies for inclusion body myositis
Sporadic Inclusion Body Myositis (IBM) remains without proven treatment, reflecting a previous lack of preclinical disease models… 
2011
2011
P71 A randomised, double-blinded, placebo-controlled pilot study assessing the safety and tolerability of Arimoclomol in sporadic inclusion body myositis (IBM)
Review
2010
Review
2010
Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis.
  • J. Phukan
  • IDrugs : the investigational drugs journal
  • 2010
  • Corpus ID: 36503653
Recent years have seen an explosion of research into increasingly prevalent neurodegenerative diseases. Arimoclomol (BRX-220… 
2010
2010
B12 Treatment with arimoclomol does not lead to rescue of motor or striatal deficits in the YAC128 mouse model of Huntington's disease
Background Huntington's Disease (HD) is an inherited neurological disorder characterised by loss of motor coordination, cognitive… 
2010
2010
PONM17 Augmentation of the heat shock response in an in vitro model of sporadic inclusion body myositis
Sporadic inclusion body myositis (IBM), the commonest myopathy acquired by those aged over 50 years, remains without proven… 
2008
2008
Improving Warfighters' Sustainment and Performance in Extreme Environmental Conditions
Abstract : In this project, we have developed and verified experimental rat models capable of reproducing physiological responses… 
2004
2004
Arimoclomol delays progression in ALS mouse model
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