arginine methyltransferase
National Institutes of Health
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Aberrant transcription‐associated RNA:DNA hybrid (R‐loop) formation often causes catastrophic conflicts during replication…
Recurrent chromosomal aberrations have led to the discovery of oncogenes or tumour suppressors involved in carcinogenesis. Here…
BackgroundProtein arginine methyltransferase 5 (PRMT5) catalyzes the formation of symmetrical dimethylation of arginine residues…
A novel aryl pyrazole series of arginine methyltransferase inhibitors has been identified. Synthesis of analogues within this…
Recent evidence points to the protein arginine methyltransferase (PRMT) family of enzymes playing critical roles in cancer. PRMT7…
BackgroundProtein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and…
Protein arginine methyltransferase 5 (PRMT5) plays multiple roles in a large number of cellular processes, and its subcellular…
Lysine and arginine methyltransferases participate in the posttranslational modification of histones and regulate key cellular…
PRMT1 is a histone methyltransferase that methylates Arg3 on histone H4. When we used siRNA to knock down PRMT1 in an erythroid…