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arachidonic acid epoxygenase activity

Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid. [http://lipidlibrary.aocs.org… 
National Institutes of Health

Papers overview

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2019
2019
Abstract LB-023: CYP monooxygenases regulate nuclear localization of ERá and mTORC1 component RagC in ER+HER2- breast cancer cells
Introduction: Cancer cell-intrinsic CYP monooxygenases promote tumor progression. In ER+ breast cancer cells, CYP3A4 is required… 
2006
2006
Induction of Renal Cytochrome P450 Arachidonic Acid Epoxygenase Activity by Dietary γ-Linolenic Acid
Dietary γ-linolenic acid (GLA), a ω-6 polyunsaturated fatty acid found in borage oil (BOR), lowers systolic blood pressure in… 
2006
2006
INDUCTION OF CYP1A AND CYP2-MEDIATED ARACHIDONIC ACID EPOXYGENATION AND SUPPRESSION OF 20-HYDROXYEICOSATETRAENOIC ACID BY IMIDAZOLE DERIVATIVES INCLUDING THE AROMATASE INHIBITOR VOROZOLE
Cytochrome P450 (P450) enzymes metabolize the membrane lipid arachidonic acid to stable biologically active epoxides… 
2006
2006
Having a heart attack? Avoid the "HETE"!
ischemia-reperfusion (I/R) injury plays a major role in the pathogenesis of cardiac complications, such as myocardial infarction… 
Highly Cited
2001
Highly Cited
2001
Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells.
CYP2J2 is abundant in human heart and its arachidonic acid metabolites, the epoxyeicosatrienoic acids (EETs), have potent… 
2001
2001
Overexpression of Cytochrome P 450 CYP 2 J 2 Protects against Hypoxia-Reoxygenation Injury in Cultured Bovine Aortic Endothelial Cells
CYP2J2 is abundant in human heart and its arachidonic acid metabolites, the epoxyeicosatrienoic acids (EETs), have potent… 
2000
2000
Adenoviral vector-mediated transfer of human heme oxygenase in rats decreases renal heme-dependent arachidonic acid epoxygenase activity.
Intravenous administration of an adenovirus human heme oxygenase (HO)-1 gene construct to rats resulted in functional expression… 
Highly Cited
1983
Highly Cited
1983
Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets.
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