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arachidonic acid epoxygenase activity

Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid. [http://lipidlibrary.aocs.org… Expand
National Institutes of Health

Papers overview

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2019
2019
Introduction: Cancer cell-intrinsic CYP monooxygenases promote tumor progression. In ER+ breast cancer cells, CYP3A4 is required… Expand
2006
2006
Dietary γ-linolenic acid (GLA), a ω-6 polyunsaturated fatty acid found in borage oil (BOR), lowers systolic blood pressure in… Expand
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2006
2006
Cytochrome P450 (P450) enzymes metabolize the membrane lipid arachidonic acid to stable biologically active epoxides… Expand
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2006
2006
ischemia-reperfusion (I/R) injury plays a major role in the pathogenesis of cardiac complications, such as myocardial infarction… Expand
Highly Cited
2001
Highly Cited
2001
CYP2J2 is abundant in human heart and its arachidonic acid metabolites, the epoxyeicosatrienoic acids (EETs), have potent… Expand
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2001
2001
CYP2J2 is abundant in human heart and its arachidonic acid metabolites, the epoxyeicosatrienoic acids (EETs), have potent… Expand
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2000
2000
Intravenous administration of an adenovirus human heme oxygenase (HO)-1 gene construct to rats resulted in functional expression… Expand
Highly Cited
1983
Highly Cited
1983
Metapyrone and eicosatetraynoic acid but not indomethacin are effective inhibitors of the secretory response of isolated rat… Expand