appendage development

The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ… (More)
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

appendage morphogenesis

Broader (1)

multicellular organism development

Papers overview

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Highly Cited
2006
Highly Cited
2006
Smad7-induced beta-catenin degradation alters epidermal appendage development.
To assess whether Smad signaling affects skin development, we generated transgenic mice in which a Smad antagonist, Smad7, was… (More)
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Highly Cited
2005
Highly Cited
2005
Functional analyses in the milkweed bug Oncopeltus fasciatus (Hemiptera) support a role for Wnt signaling in body segmentation but not appendage development.
Specification of the proximal-distal (PD) axis of insect appendages is best understood in Drosophila melanogaster, where… (More)
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Highly Cited
2002
Highly Cited
2002
The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development.
Dlx homeobox genes are mammalian homologs of the Drosophila Distal-less (Dll) gene. The Dlx/Dll gene family is of ancient origin… (More)
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Highly Cited
2002
Highly Cited
2002
Hox repression of a target gene: extradenticle-independent, additive action through multiple monomer binding sites.
Homeotic (Hox) genes regulate the identity of structures along the anterior-posterior axis of most animals. The low DNA-binding… (More)
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2002
2002
A complex role for distal-less in crustacean appendage development.
The developing leg of Drosophila is initially patterned by subdivision of the leg into proximal and distal domains by the… (More)
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Highly Cited
2002
Highly Cited
2002
Shh-Bmp2 signaling module and the evolutionary origin and diversification of feathers.
To examine the role of development in the origin of evolutionary novelties, we investigated the developmental mechanisms involved… (More)
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2000
2000
Distinct roles of the homeotic genes Ubx and abd-A in beetle embryonic abdominal appendage development.
Insects are easily distinguishable by the absence of legs on the adult abdomen. Studies performed on the Dipteran, Drosophila… (More)
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Highly Cited
1999
Highly Cited
1999
Ultrabithorax function in butterfly wings and the evolution of insect wing patterns
BACKGROUND . The morphological and functional evolution of appendages has played a critical role in animal evolution, but the… (More)
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Highly Cited
1997
Highly Cited
1997
The homeobox gene Distal-less induces ventral appendage development in Drosophila.
This study investigates the role of the homeobox gene Distal-less (Dll) in the development of the legs, antennae, and wings of… (More)
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Highly Cited
1990
Highly Cited
1990
Wing formation in Drosophila melanogaster requires decapentaplegic gene function along the anterior-posterior compartment boundary.
Previous analyses of the decapentaplegic (dpp) gene in Drosophila melanogaster have suggested that its product, a polypeptide of… (More)
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