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antofloxacin hydrochloride

National Institutes of Health

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antofloxacin

Papers overview

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2012
2012
Dose findings of antofloxacin hydrochloride for treating bacterial infections in an early clinical trial using PK-PD parameters in healthy volunteers
Aim:To find an appropriate dose regimen of the novel antibacterial agent antofloxacin for a phase II clinical trial using a… 
2011
2011
Pharmacokinetic study of single and multiple oral dose administration of antofloxacin hydrochloride in healthy male volunteers.
BACKGROUND A new fluroquinolone antibacterial agent, antofloxacin hydrochloride, developed in China, is an 8-NH(2) derivant of… 
2011
2011
Pharmacokinetics of antofloxacin hydrochloride in healthy male subjects after multiple intravenous dose administration
  • J. WangY. Xiao T. Li
  • Xenobiotica; the fate of foreign compounds in…
  • 2011
  • Corpus ID: 23942259
The purpose of the study was to evaluate pharmacokinetic characteristics of antofloxacin hydrochloride, a new fluoroquinolone… 
2010
2010
A Phase II Study of Antofloxacin Hydrochloride, a Novel Fluoroquinolone, for the Treatment of Acute Bacterial Infections
Aims: To evaluate the clinical and bacterial efficacies and the safety of antofloxacin hydrochloride tablets in the treatment of… 
2010
2010
The action of a novel fluoroquinolone antibiotic agent antofloxacin hydrochloride on human-ether-à-go-go-related gene potassium channel.
The administration of certain fluoroquinolone antibacterials has recently been linked to QT interval prolongation, raising the… 
2010
2010
Pharmacokinetics of antofloxacin hydrochloride, a novel fluoroquinolone, after single-dose intravenous administration in healthy Chinese male volunteers
  • J. WangY. Xiao T. Li
  • Xenobiotica; the fate of foreign compounds in…
  • 2010
  • Corpus ID: 19325471
The purpose of the study was to evaluate the pharmacokinetic characteristics of a single, intravenous dose of antofloxacin… 
2008
2008
Pharmacokinetics of antofloxacin hydrochloride, a new fluoroquinolone antibiotic, after single oral dose administration in Chinese healthy male volunteers
Antofloxacin hydrochloride is a newly developed fluoroquinolone antibacterial in China, which has comparable in vitro and animal… 
2008
2008
Pharmacokinetics/pharmacodynamics of antofloxacin hydrochloride in a neutropenic murine thigh model of Staphylococcus aureus infection
AbstractAim:Antofloxacin hydrochloride is a new fluoroquinolone antibiotic with broad-spectrum in vitro activity. Using the… 
2008
2008
Tolerability and pharmacokinetics of antofloxacin hydrochloride after multiple oral dose administration in healthy Chinese male volunteers.
OBJECTIVE To evaluate the tolerability and pharmacokinetics characteristics of antofloxacin hydrochloride, a fluoroquinolone… 
2008
2008
Tolerance of antofloxacin hydrochloride after ascending single oral dose administration in healthy male volunteers
Objective To evaluate the safety and tolerance of single dose antofloxacin hydrochloride oral administration in healthy male… 
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