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anterior neuropore closure

The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube… Expand
National Institutes of Health

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neuropore closure

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Inhibition of transmethylation disturbs neurulation in chick embryos.
Periconceptional folic acid supplementation can reduce the occurrence of neural tube defects. A low folate status will result in… Expand
2002
2002
Evidence for Ras-dependent signal transduction in phenytoin teratogenicity.
Reactive oxygen species (ROS) can transduce intracellular signals or damage macromolecules, including mutational activation of… Expand
2000
2000
Hairy backs, tails and dimples
The term ‘spinal dysraphism’ encompasses a hetero-geneous group of congenital anomalies of spinal corddevelopment characterized… Expand
Highly Cited
1999
Highly Cited
1999
Differential sensitivity of the SWV and C57BL/6 mouse strains to the teratogenic action of single administrations of cadmium given throughout the period of anterior neuropore closure.
When administered to mice during gestation, the heavy metal, cadmium, is known to induce malformations of the neural tube… Expand
Highly Cited
1997
Highly Cited
1997
Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis.
A mouse embryo culture model was used to determine whether embryonic prostaglandin H synthase (PHS)-catalyzed bioactivation and… Expand
1997
1997
UDP-glucuronosyltransferase-mediated protection against in vitro DNA oxidation and micronucleus formation initiated by phenytoin and its embryotoxic metabolite 5-(p-hydroxyphenyl)-5-phenylhydantoin.
UDP-Glucuronosyltransferases (UGTs) are important in the elimination of most xenobiotics, including 5-(p-hydroxyphenyl)-5… Expand
1994
1994
Evidence for embryonic peroxidase-catalyzed bioactivation and glutathione-dependent cytoprotection in phenytoin teratogenicity: modulation by eicosatetraynoic acid and buthionine sulfoximine in…
Phenytoin teratogenicity may result from embryonic, peroxidase-catalyzed bioactivation of phenytoin to a toxic reactive free… Expand
Highly Cited
1992
Highly Cited
1992
Patterns of ethanol-induced cell death in the developing nervous system of mice; Neural fold states through the time of anterior neural tube closure
  • L. Kotch, K. Sulik
  • International Journal of Developmental…
  • 1992
    • Corpus ID: 21438575
Vital staining and routine histological analyses of mouse embryos 12 h after acute maternal ethanol administration (2.9 g/kg… Expand
1989
1989
Abnormal neurulation induced by 7-hydroxy-2-acetylaminofluorene and acetaminophen: evidence for catechol metabolites as proximate dysmorphogens.
Direct additions to culture media of either acetaminophen (APAP) or 7-hydroxy-2-acetylaminofluorene (7-OH-AAF) resulted in… Expand
1983
1983
Early morphological abnormalities in splotch mouse embryos and predisposition to gene- and retinoic acid-induced neural tube defects.
Genetic and environmental factors contribute to an individual's neural tube defect liability. In the mouse, the gene mutation… Expand
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