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ansamycin biosynthetic process

Known as: ansamycin biosynthesis, ansamycin formation, ansamycin synthesis 
The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic… Expand
National Institutes of Health

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2019
2019
Ansamycins are a class of macrolactams with diverse bioactivities, characterized by the unique 3-amino-5-hydroxybenzoic acid… Expand
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Highly Cited
2017
Highly Cited
2017
BackgroundChronic rhinosinusitis (CRS) is a heterogeneous disease characterized by persistent sinonasal inflammation and sinus… Expand
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2010
2010
The plant-derived maytansinoids 4[1] and their microbial counterparts, the ansamitocins P-2 to P-4 5-7 (Figure 1) [2] exert… Expand
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2005
2005
Stable, homotypic mutants of Chlamydia trachomatis for which MICs of rifampin and rifalazil are elevated were isolated by serial… Expand
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2005
2005
Heat shock protein 90 (Hsp90) is a molecular chaperone that promotes the conformational maturation of numerous client proteins… Expand
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1998
1998
  • Sean P. Bohen
  • Molecular and cellular biology
  • 1998
  • Corpus ID: 28878092
The ubiquitous molecular chaperone Hsp90 acts in concert with a cohort of associated proteins to facilitate the functional… Expand
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1997
1997
Geldanamycin belongs to the family of benzoquinoid ansamycin tyrosine-kinase inhibitors. We have examined its effects on Her-2… Expand
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Highly Cited
1994
Highly Cited
1994
Herbimycin A, a benzoquinoid ansamycin, is widely used as an inhibitor of tyrosine kinases. We have examined the effects of… Expand
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1994
1994
Herbimycin A, a benzoquinoid ansamycin antibiotic, has been shown to reverse the oncogenic phenotype of p60v-src transformed… Expand
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