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ansamycin biosynthetic process

Known as: ansamycin biosynthesis, ansamycin formation, ansamycin synthesis 
The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic… Expand
National Institutes of Health

Papers overview

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2019
2019
Ansamycins are a class of macrolactams with diverse bioactivities, characterized by the unique 3-amino-5-hydroxybenzoic acid… Expand
Highly Cited
2017
Highly Cited
2017
BackgroundChronic rhinosinusitis (CRS) is a heterogeneous disease characterized by persistent sinonasal inflammation and sinus… Expand
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2010
2010
The plant-derived maytansinoids 4[1] and their microbial counterparts, the ansamitocins P-2 to P-4 5-7 (Figure 1) [2] exert… Expand
2005
2005
ABSTRACT Stable, homotypic mutants of Chlamydia trachomatis for which MICs of rifampin and rifalazil are elevated were isolated… Expand
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2005
2005
Heat shock protein 90 (Hsp90) is a molecular chaperone that promotes the conformational maturation of numerous client proteins… Expand
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Highly Cited
1998
Highly Cited
1998
  • S. Bohen
  • Molecular and Cellular Biology
  • 1998
  • Corpus ID: 28878092
ABSTRACT The ubiquitous molecular chaperone Hsp90 acts in concert with a cohort of associated proteins to facilitate the… Expand
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Highly Cited
1997
Highly Cited
1997
Geldanamycin belongs to the family of benzoquinoid ansamycin tyrosine‐kinase inhibitors. We have examined its effects on Her‐2… Expand
Highly Cited
1994
Highly Cited
1994
Herbimycin A, a benzoquinoid ansamycin, is widely used as an inhibitor of tyrosine kinases. We have examined the effects of… Expand
1994
1994
Herbimycin A, a benzoquinoid ansamycin antibiotic, has been shown to reverse the oncogenic phenotype of p60v-src transformed… Expand