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ansamycin biosynthetic process

Known as: ansamycin biosynthesis, ansamycin formation, ansamycin synthesis 
The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic… 
National Institutes of Health

Papers overview

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2018
2018
Overexpression of the pathway-specific positive regulator gene mas13 activated the cryptic gene cluster mas, resulting in the… 
2013
2013
Mangrove-derived actinomycetes are promising sources of bioactive natural products. In this study, using homologous screening of… 
2010
2010
The plant-derived maytansinoids 4[1] and their microbial counterparts, the ansamitocins P-2 to P-4 5-7 (Figure 1) [2] exert… 
2005
2005
ABSTRACT Stable, homotypic mutants of Chlamydia trachomatis for which MICs of rifampin and rifalazil are elevated were isolated… 
2005
2005
Heat shock protein 90 (Hsp90) is a molecular chaperone that promotes the conformational maturation of numerous client proteins… 
Highly Cited
1998
Highly Cited
1998
ABSTRACT The ubiquitous molecular chaperone Hsp90 acts in concert with a cohort of associated proteins to facilitate the… 
Highly Cited
1997
Highly Cited
1997
Geldanamycin belongs to the family of benzoquinoid ansamycin tyrosine‐kinase inhibitors. We have examined its effects on Her‐2… 
Highly Cited
1994
Highly Cited
1994
Herbimycin A, a benzoquinoid ansamycin, is widely used as an inhibitor of tyrosine kinases. We have examined the effects of…