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amenamevir

A novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2. Amenamenir stabilizes the… 
National Institutes of Health

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ASP2151

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Pharmacokinetics and Dialyzability of a Single Oral Dose of Amenamevir, an Anti-Herpes Drug, in Hemodialysis Patients
Introduction Amenamevir (ASP2151), a herpesvirus helicase-primase inhibitor, is currently used for the treatment of herpes zoster… 
2019
2019
Efficacy of amenamevir for the treatment of herpes zoster in an immunocompromised patient: Report of a case
1 Gilden DH, Kleinshmidt BK, LaGuardia JL, Mahalingham R, Cohrs RJ. Neurologic complications of the reactivation of varicella… 
Review
2018
Review
2018
Antiviral Drugs Against Alphaherpesvirus.
The discovery of acyclovir and penciclovir has led to the development of a successful systemic therapy for treating herpes… 
2016
2016
Integrative pharmacokinetic-pharmacodynamic modeling and simulation of amenamevir (ASP2151) for treatment of recurrent genital herpes.
2015
2015
IMS-P 22 Discovery of Amenamevir ( ASP 2151 ) , a Helicase-Primase Inhibitor as an Antiviral Drug against Varicella-Zoster Virus and Herpes Simplex Virus Types 1 and 2 ○
2014
2014
Statistical analysis of Amenamevir (ASP2151) between pharmacokinetics and clinical efficacies with non‐linear effect model for the treatment of genital herpes
Amenamevir is the international non‐proprietary name for ASP2151 synthesized by Astellas Pharma, Inc. It is a structurally novel… 
Review
2013
Review
2013
A short commentary on the review by Weller and Kuchta: the DNA helicase–primase complex as a target for herpes virus infection
For anyone new to the field of herpes virus DNA replication may I point you to the perfect introduction to this subject by the… 
2013
2013
新規抗ヘルペスウイルス剤 amenamevir (ASP2151) の臨床効果予測に関する研究
2012
2012
Pharmacokinetics and Pharmacodynamics of ASP2151, a Helicase-Primase Inhibitor, in a Murine Model of Herpes Simplex Virus Infection
ABSTRACT ASP2151 (amenamevir) is a helicase-primase inhibitor against herpes simplex virus 1 (HSV-1), HSV-2, and varicella zoster… 
2010
2010
ASP 2151 , a novel helicase – primase inhibitor , possesses antiviral activity against varicella – zoster virus and herpes simplex virus types 1 and 2
Methods: The inhibitory effect of ASP2151 on enzymatic activities associated with a recombinant HSV-1 helicase–primase complex… 
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