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amenamevir

A novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2. Amenamenir stabilizes the… Expand
National Institutes of Health

Papers overview

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2017
2017
Amenamevir is a potent helicase–primase inhibitor and a novel class of antiviral agent other than nucleoside compounds, such as… Expand
Review
2017
Review
2017
Valacyclovir and famciclovir enabled successful systemic therapy for treating herpes simplex virus (HSV) and varicella zoster… Expand
2017
2017
IntroductionAmenamevir (ASP2151) is a nonnucleoside antiherpesvirus compound available for the treatment of varicella–zoster… Expand
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2017
2017
&NA; The antiherpetic drugs acyclovir (ACV, valaciclovir) and penciclovir (famciclovir) are phosphorylated by viral thymidine… Expand
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Review
2016
Review
2016
Herpes simplex virus (HSV) types 1 and 2 can cause infections with clinical manifestations ranging from benign and generally self… Expand
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2013
2013
ASP2151 (amenamevir) is a helicase-primase complex inhibitor with antiviral activity against herpes simplex virus HSV-1, HSV-2… Expand
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2012
2012
ABSTRACT ASP2151 (amenamevir) is a helicase-primase inhibitor against herpes simplex virus 1 (HSV-1), HSV-2, and varicella zoster… Expand
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2012
2012
ASP2151 is an antiherpes agent targeting the helicase-primase complex of herpes simplex virus (HSV)-1, HSV-2, and varicella… Expand
Highly Cited
2010
Highly Cited
2010
OBJECTIVES To evaluate and describe the anti-herpesvirus effect of ASP2151, amenamevir, a novel non-nucleoside oxadiazolylphenyl… Expand
2010
2010
Methods: The inhibitory effect of ASP2151 on enzymatic activities associated with a recombinant HSV-1 helicase–primase complex… Expand
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