Skip to search formSkip to main contentSkip to account menu

alsterpaullone

Known as: 9-nitro-7,12-dihydroindolo(3,2-d)(1)benzazepin-6(5H)-one 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

BenzazepinesIndoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Antitumor activity of cyclin‐dependent kinase inhibitor alsterpaullone in Epstein‐Barr virus‐associated lymphoproliferative disorders
Epstein‐Barr virus (EBV) is a well‐established tumor virus that has been implicated in a wide range of immunodeficiency… 
2018
2018
Alsterpaullone induces apoptosis of HepG2 cells via a p38 mitogen-activated protein kinase signaling pathway
Alsterpaullone (Alp) is a small-molecule inhibitor that targets cyclin-dependent kinases to inhibit tumor cell activity. However… 
2015
2015
Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma
Advances in the molecular biology of medulloblastoma revealed four genetically and clinically distinct subgroups. Group 3… 
2014
2014
High-Throughput Screening Reveals Alsterpaullone, 2-Cyanoethyl as a Potent p27Kip1 Transcriptional Inhibitor
p27Kip1 is a cell cycle inhibitor that prevents cyclin dependent kinase (CDK)/cyclin complexes from phosphorylating their targets… 
2013
2013
Alsterpaullone, a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells through Apoptosis-Inducing Effect
Alsterpaullone, a small molecule cyclin-dependent kinase (CDK) inhibitor, regulates the cell cycle progression. Beyond death… 
2010
2010
Drosophila notal bristle as a novel assessment tool for pathogenic study of Tau toxicity and screening of therapeutic compounds.
2007
2007
Cyclosporine A- and FK506-induced apoptosis in PC12 cells
The purpose of this study was to examine, using glycogen synthase kinase (GSK) inhibitors, whether GSK-3 is involved in… 
2006
2006
Thapsigargin-induced apoptosis was prevented by glycogen synthase kinase-3 inhibitors in PC12 cells
Highly Cited
2004
Highly Cited
2004
Down-regulation of Survivin in Nitric Oxide-induced Cell Growth Inhibition and Apoptosis of the Human Lung Carcinoma Cells*
Survivin is expressed in most tumor cells and has been associated with both anti-apoptosis and mitotic progression. However, the… 
Highly Cited
2003
Highly Cited
2003
Alsterpaullone, a novel cyclin‐dependent kinase inhibitor, induces apoptosis by activation of caspase‐9 due to perturbation in mitochondrial membrane potential
The majority of human neoplasms have aberrations in the retinoblastoma pathway due to hyperactivation of cyclin‐dependent kinases… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)