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alpha-2,8-sialyltransferase

 
National Institutes of Health

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Topic mentions per year

1995-2009
012319952009

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2009
2009
In vitro analysis of glial cell function in ganglioside-deficient mice.
Gangliosides are a family of sialic acid-containing glycosphingolipids highly enriched in neuronal and glial membranes, where… (More)
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2005
2005
GD3 synthase gene knockout mice exhibit thermal hyperalgesia and mechanical allodynia but decreased response to formalin-induced prolonged noxious stimulation.
Gangliosides are a family of sialic acid-containing glycosphingolipids that are highly enriched in the mammalian nervous system… (More)
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2002
2002
Beta-amyloid-induced synthesis of the ganglioside GD3 is a requisite for cell cycle reactivation and apoptosis in neurons.
We have shown that cortical neurons challenged with toxic concentrations of beta-amyloid peptide (betaAP) enter the S phase of… (More)
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1995
1995
Purification of an alpha-2,8-sialyltransferase, a potential initiating enzyme for the biosynthesis of polysialic acid in human neuroblastoma cells.
alpha-2,8-Sialyltransferase has been purified from human neuroblastoma CHP-134 cells greater than 2900-fold. The key step in the… (More)
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1995
1995
A novel method to co-localize glycosaminoglycan-core oligosaccharide glycosyltransferases in rat liver Golgi. Co-localization of galactosyltransferase I with a sialyltransferase.
4-Methylumbelliferyl-beta-xyloside (Xyl beta MU) primes glycosaminoglycan synthesis by first serving as an acceptor for the… (More)
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1995
1995
Regulation of glycolipid synthesis in HL-60 cells by antisense oligodeoxynucleotides to glycosyltransferase sequences: effect on cellular differentiation.
Treatment of the human promyelocytic leukemia cell line HL-60 with antisense oligodeoxynucleotides to UDP-N-acetylgalactosamine… (More)
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