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aleglitazar

A dual peroxisome proliferator-activated receptor (PPAR) agonist, with hypoglycemic activity. Aleglitazar binds to both PPARalpha and PPARgamma and… Expand
National Institutes of Health

Papers overview

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2016
2016
Adipose tissue inflammation is a mechanistic link between obesity and its related sequelae, including insulin resistance and type… Expand
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2014
2014
IMPORTANCE No therapy directed against diabetes has been shown to unequivocally reduce the excess risk of cardiovascular… Expand
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Review
2014
Review
2014
The epidemic of obesity and its association with insulin resistance, glucose intolerance, hypertension, and dyslipidemia… Expand
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Review
2013
Review
2013
  • J Fruchart
  • Cardiovascular Diabetology
  • 2013
  • Corpus ID: 5776869
Dyslipidemia is a major risk factor for cardiovascular (CV) disease – the primary cause of death, worldwide. Although reducing… Expand
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2012
2012
Abstract Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors that control the… Expand
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2011
2011
BackgroundGlycemic control and management of dyslipidemia to reduce cardiovascular risk are major therapeutic goals in… Expand
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2011
2011
BACKGROUND Aleglitazar is a new, balanced dual peroxisome proliferator-activated receptor (PPAR)α/γ agonist designed to optimize… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Despite previous reports of potential adverse cardiovascular effects of peroxisome proliferator-activated receptor… Expand
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2009
2009
Design, synthesis, and SAR of novel alpha-alkoxy-beta-arylpropionic acids as potent and balanced PPARalphagamma coagonists are… Expand
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