albitiazolium
National Institutes of Health
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During the intraerythrocytic asexual cycle malaria parasites acquire nutrients and other solutes through a broad selectivity…
ABSTRACT Albitiazolium is the lead compound of bisthiazolium choline analogues and exerts powerful in vitro and in vivo…
Plasmodium falciparum is responsible for severe malaria which is one of the most prevalent and deadly infectious diseases in the…
Choline analogues such as bis-thiazolium salts are thought to inhibit choline transport into Plasmodium-infected erythrocytes…
BACKGROUND AND PURPOSE Choline analogues, a new type of antimalarials, exert potent in vitro and in vivo antimalarial activity…
Emerging resistance against well-established anti-malaria drugs warrants the introduction of new therapeutic agents with original…