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alamifovir
Known as:
Bis(2,2,2-trifluoroethyl) ((2-{2-amino-6-((4-methoxyphenyl)sulfanyl)-9H-purin-9-yl}ethoxy)methyl)phosphonate
A purine nucleotide analog prodrug with activity against wild-type and lamivudine-resistant hepatitis B virus (HBV). Alamifovir acts by inhibiting…
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National Institutes of Health
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LY 582563
MCC 478
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Determination of alamifovir disoproxil fumarate and its active metabolite 602076 in rat plasma by LC-MS/MS: application to a pharmacokinetic study.
Pingping Zhang
,
Jifen Guo
,
Fanhua Meng
,
Lu Sun
,
Bohua Zhong
,
Yimin Zhao
Journal of Pharmaceutical and Biomedical Analysis
2012
Corpus ID: 28588000
2011
2011
etermination of alamifovir disoproxil fumarate and its active metabolite 02076 in rat plasma by LC – MS / MS : Application to a pharmacokinetic study
ing Zhanga
,
Jifen Guoa
,
F. Menga
,
L. Sunb
,
Bohua Zhonga
,
Yimin Zhaoa
2011
Corpus ID: 21728158
Alamifovir disoproxil fumarate (ADF) is a novel ester prodrug of alamifovir, which is currently as a promising antiviral…
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2010
2010
Design,synthesis and biological activity of prodrugs of alamifovir analogs
Zhong Bo-hua
2010
Corpus ID: 100761768
Aim To design and synthesize new alamifovir analogs prodrugs.Methods The target compounds were synthesized via chloromethylation…
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2005
2005
Clinical Pharmacokinetics of Alamifovir and Its Metabolites
C. Chan
,
E. Abu-Raddad
,
+8 authors
S. Wise
Antimicrobial Agents and Chemotherapy
2005
Corpus ID: 40205497
ABSTRACT Alamifovir, a purine nucleotide analogue prodrug, and its hydrolyzed derivatives have shown preclincal efficacy activity…
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2004
2004
Safety and efficacy of alamifovir in patients with chronic hepatitis B virus infection.
D. Soon
,
S. Lowe
,
C. Teng
,
K. Yeo
,
J. McGill
,
S. Wise
Journal of Hepatology
2004
Corpus ID: 45968456
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