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aflatoxin B1 metabolic process

Known as: aflatoxin B1 metabolism 
The chemical reactions and pathways involving aflatoxin B1, a potent hepatotoxic and hepatocarcinogenic mycotoxin produced by various species from… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Mechanisms of butylated hydroxytoluene chemoprevention of aflatoxicosis--inhibition of aflatoxin B1 metabolism.
Chemoprevention of toxicoses and/or cancer through the use of nutrients or pharmacologic compounds is the subject of intense… Expand
2002
2002
Effects of bicyclol on aflatoxin B1 metabolism and hepatotoxicity in rats.
  • Hong Lu, Y. Li
  • Acta pharmacologica Sinica
  • 2002
    • Corpus ID: 38881432
AIM To study the effect of new antihepatitis drug, bicyclol, on the metabolism and hepatotoxicity of aflatoxin B1 (AFB1) in rats… Expand
2002
2002
EFFECTS OF SATURATED A N D UNSATURATED DIETARY FAT ON AFLATOXIN BI METABOLISM
-Male Fisher 344 rats were fed diets containing either 20~ corn oil, 20~ coconut oil or 18~ coconut oil plus 2~ corn oil for 3 wk… Expand
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Highly Cited
1998
Highly Cited
1998
Dietary carotenoids inhibit aflatoxin B1-induced liver preneoplastic foci and DNA damage in the rat: role of the modulation of aflatoxin B1 metabolism.
To study the effects of carotenoids on the initiation of liver carcinogenesis by aflatoxin B1 (AFB1), male weanling rats were fed… Expand
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Highly Cited
1997
Highly Cited
1997
Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism.
A range of potential chemoprotective agents, most of them natural dietary constituents, has been examined for ability to modulate… Expand
Highly Cited
1995
Highly Cited
1995
Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture.
Dithiolethiones are thought to act as potent chemoprotective agents against aflatoxin B1 (AFB1)-induced hepatocarcinogenesis in… Expand
Highly Cited
1990
Highly Cited
1990
Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver.
Liver cancer is a major cause of premature death in many areas of Africa and Asia and its incidence is strongly correlated with… Expand
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1988
1988
The genetics of aflatoxin B1 metabolism. Association of the induction of aflatoxin B1-4-hydroxylase with the transcriptional activation of cytochrome P3-450 gene.
The association between murine cytochrome P3-450 and hepatic aflatoxin B1-4-hydroxylase, a cytochrome P-450-dependent enzyme… Expand
1986
1986
The in vitro metabolism of aflatoxin B1 catalyzed by hepatic microsomes isolated from control or 3-methylcholanthrene-stimulated rats and quail.
The rate of microsomal metabolism of aflatoxin B1 (AFB1) by the male quail hepatic microsomal polysubstrate monooxygenase P-450… Expand
1984
1984
Effects of saturated and unsaturated dietary fat on aflatoxin B1 metabolism.
Male Fisher 344 rats were fed diets containing either 20% corn oil, 20% coconut oil or 18% coconut oil plus 2% corn oil for 3 wk… Expand
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