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adibendan

Known as: 7,7-dimethyl-2-(4-pyridyl)-6,7-dihydro-3H,5H pyrrolo (2,3-f)benz-imidazol-6-one, Pyrrolo(2,3-f)benzimidazol-6(1H)-one, 5,7-dihydro-7,7-dimethyl-2-(4-pyridinyl)- 
 
National Institutes of Health

Papers overview

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2004
2004
SummaryThe present study was performed to compare the effects of the new positive inotropic phosphodiesterase III inhibitors… Expand
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2004
2004
Summary1.The effects of adibendan (BM 14.478; 7,7-dimethyl-2-(4-pyridyl)-6,7-dihydro-3H,5H-pyrrolo[2,3-fl benzimidazole-6-one) on… Expand
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1992
1992
Four cyclic AMP (cAMP)-phosphodiesterases (PDE) belonging to families I, II, III and IV were identified in homogenates from human… Expand
1992
1992
Positive inotropic effects of phosphodiesterase inhibitors like 3-isobutyl-1-methylxanthine (IBMX), pimobendan, adibendan… Expand
1990
1990
1 This study was performed to investigate whether cardiac positive inotropic as well as peripheral vasodilator properties of… Expand
1989
1989
We previously reported the structure-activity relationships (SAR) of adibendan (1), a potent and long-acting cardiotonic. This… Expand
1989
1989
Several cardiotonic agents (MCI-154, sulmazole, pimobendan and adibendan) were examined for their ability to influence Ca2… Expand
1989
1989
Myocardial contractile force may be altered not only by changing intracellular free Ca2+ but also by increasing or decreasing the… Expand
1989
1989
Abstract Phosphodiesterase inhibitors show promise in the treatment of patients with severe congestive heart failure (CHF). 1,2… Expand
1988
1988
Summary: BM 14.478 (7,7-dimethyl-2-(4-pyridyl)-6,7-dihydro-3H,5H pyrrolo[2,3-f]benz-imidazol-6-one) was investigated in several… Expand