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adenylosuccinate synthase activity

Known as: IMP--aspartate ligase activity, succino-AMP synthetase activity, adenylosuccinate synthetase activity 
Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate. [EC:6.3.4.4, RHEA:15756]
National Institutes of Health

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Adenylosuccinate Synthase

Papers overview

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2006
2006
Nucleotide mutations in purA gene and pur operon promoter discovered in guanosine- and inosine-producing Bacillus subtilis strains
The promoter region of the pur operon, which contains 12 genes for inosine monophosphate biosynthesis from… 
2003
2003
Adenylosuccinase Activity in Human and Rabbit
Adenylosuccinase activity was demonstrated in lysates prepared from mature human and rabbit erythrocytes by investigating both… 
2003
2003
Adenylosuccinase Activity in Human and Rabbit Erythrocyte Lysates
Adenylosuccinase activity was demonstrated in lysates prepared from mature human and rabbit erythrocytes by investigating both… 
1984
1984
Intermediary purine-metabolizing enzymes from the cytosol of Dictyostelium discoideum monitored by high-performance liquid chromatography.
1983
1983
Effect of acidosis and uninephrectomy on isozymes of adenylosuccinate synthetase in rat kidney.
1983
1983
Genetic studies on the role of the nucleoside transport function in nucleoside efflux, the inosine cycle, and purine biosynthesis
A mutant clone (AU-100) which is 90% deficient in adenylosuccinate synthetase activity was characterized from wild-type murine… 
1978
1978
Effect of Hadacidin on Growth and Adenylosuccinate Synthetase Activity of Dictyostelium discoideum
The growth of the eucaryotic microorganism Dictyostelium discoideum in liquid culture was completely inhibited by the aspartic… 
1978
1978
Characterization of a guanine‐sensitive mutant defective in adenylo‐succinate synthetase activity
A contingent auxotrophic mutant of CHO‐Kl cell is described. This mutant grow in minimal medium. Its growth is inhibited by the… 
1976
1976
Study on the regulatory role of fructose-1,6-diphosphate in the formation of AMP in rat skeletal muscle. A mechanism for synchronization of glycolysis and the purine nucleotide cycle.
1974
1974
Human adenylosuccinate synthetase. Partial purification, kinetic and regulatory properties of the enzyme from placenta.
Abstract Human adenylosuccinate synthetase (IMP:aspartate ligase (GDP) EC 6.3.4.4) has been purified 110-fold from placenta. The… 
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