adalimumab

Known as: antibody d2e7, Immunoglobulin G1, anti-(human tumor necrosis factor) (human monoclonal D2E7 heavy chain), disulfide with human monoclonal D2E7 light chain, dimer, Adalimumab [Chemical/Ingredient] 
A recombinant, human IgG1 monoclonal antibody directed against tumor necrosis factor-alpha (TNF-alpha), with immunomodulating activity. Upon… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
1874 Sleep duration and quality are associated with immune markers, self-rated health, and mortality in a large cohort (NHANES… (More)
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Review
2017
Review
2017
Recent insights in rheumatoid arthritis (RA) necessitated updating the European League Against Rheumatism (EULAR) RA management… (More)
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Highly Cited
2011
Highly Cited
2011
CONTEXT Short-term data on the immunogenicity of monoclonal antibodies showed associations between the development of antidrug… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND & AIMS This study evaluated the efficacy and safety of adalimumab, a fully human, anti-tumor necrosis factor… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Adalimumab induced clinical remission after four weeks in patients with active Crohn's disease in the CLASSIC I trial… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND A substantial proportion of patients with rheumatoid arthritis (RA) do not respond, or lose initial response, to… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To compare the efficacy and safety of adalimumab plus methotrexate (MTX) versus MTX monotherapy or adalimumab… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS Tumor necrosis factor blockade has been shown to be an effective treatment strategy in Crohn's disease (CD… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Tumor necrosis factor (TNF) is an important proinflammatory cytokine that mediates inflammatory synovitis and articular… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE To evaluate the efficacy and safety of adalimumab (D2E7), a fully human monoclonal tumor necrosis factor alpha antibody… (More)
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