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activator of CREM in testis (ACT)

Known as: CREM activator, ACT, LIM-only protein, ACT 
 
National Institutes of Health

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2016
2016
ICER is requisite for Th17 differentiation
Inducible cAMP early repressor (ICER) has been described as a transcriptional repressor isoform of the cAMP response element… Expand
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2016
2016
Cardiac expression of the CREM repressor isoform CREM-IbΔC-X in mice leads to arrhythmogenic alterations in ventricular cardiomyocytes
Chronic β-adrenergic stimulation is regarded as a pivotal step in the progression of heart failure which is associated with a… Expand
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2016
2016
Towards an Integrated Value Adding Management Model for FM and CREM
Purpose: To present an integrated process model of adding value by Facilities Management (FM) and Corporate Real Estate… Expand
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Highly Cited
2014
Highly Cited
2014
Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model.
BACKGROUND The progression of atrial fibrillation (AF) from paroxysmal to persistent forms remains a major clinical challenge… Expand
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2013
2013
Novel aqueous nano-scaled formulations of oleic acid stabilized hydrophobic superparamagnetic iron oxide nanocrystals
Background: Novel aqueous nano-scaled formulations were developed for hydrophobic oleic acid stabilized monodisperse… Expand
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2011
2011
Enhanced oral bioavailability of tacrolimus in rats by self-microemulsifying drug delivery systems
A new self-microemulsifying drug delivery system (SMEDDS) has been developed to increase the solubility, dissolution rate and… Expand
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Highly Cited
2004
Highly Cited
2004
Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase
A transgenic mouse strain with early and uniform expres sion of the Cre site-specific recombinase is described. In this strain… Expand
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2002
2002
Novel leader exons of the cyclic adenosine 3',5'-monophosphate response element modulator (CREM) gene, transcribed from promoters P3 and P4, are highly testis-specific in primates.
Testicular expression of CREM is essential for spermatogenesis in the mouse. From a monkey testis cDNA library we isolated a CREM… Expand
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2000
2000
Novel cyclic adenosine 3',5'-monophosphate (cAMP) response element modulator theta isoforms expressed by two newly identified cAMP-responsive promoters active in the testis.
cAMP signaling contributes to the control of the developmental progression of germ cells during the spermatogenic cycle. Genes… Expand
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1995
1995
An intron facilitates activation of the calspermin gene by the testis-specific transcription factor CREM tau.
Calspermin is a high affinity Ca2+/calmodulin binding protein that is found only in postmeiotic male germ cells. Our previous… Expand
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