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activating transcription factor 1

Known as: Activating Transcription Factor-1, Transcription Factor, ATF1, Activating Transcription Factor 1 [Chemical/Ingredient] 
An activating transcription factor that regulates expression of a variety of genes including C-JUN GENES and TRANSFORMING GROWTH FACTOR BETA2.
National Institutes of Health

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Related topics

11 relations
ATF1 geneCyclic AMP-Dependent Transcription Factor ATF-1In BloodProcess of secretion

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atf1 protein, S pombe

Papers overview

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Highly Cited
2008
Highly Cited
2008
The AP-1 site is essential for the promoter activity of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme: Possible involvement of the ERK1/2-JunB pathway.
Review
2001
Review
2001
Targeting the ATF-1/CREB transcription factors by single chain Fv fragment in human melanoma: potential modality for cancer therapy.
Activating transcription factor-1 (ATF-1) and cAMP-responsive element (CRE)-binding protein (CREB) have been implicated in cAMP… 
Highly Cited
2000
Highly Cited
2000
Loss of expression of the ubiquitous transcription factor cAMP response element-binding protein (CREB) and compensatory overexpression of the activator CREMtau in the human adrenocortical cancer cell…
The pituitary hormone ACTH, acting through the cAMP pathway, plays a key role in proliferation and differentiation of the adrenal… 
2000
2000
The promoter of human acetylcholinesterase is activated by a cyclic adenosine 3′,5′-monophosphate-dependent pathway in cultured NG108–15 neuroblastoma cells
Highly Cited
2000
Highly Cited
2000
Transcriptional Regulation of Human 11β-Hydroxylase (hCYP11B1).
Steroid 11β-hydroxylase is a mitochondrial enzyme that catalyzes the conversion of deoxycortisol to cortisol. The gene encoding… 
Highly Cited
1999
Highly Cited
1999
Transcriptional Regulation of the Transforming Growth Factor-β2 Promoter by cAMP-responsive Element-binding Protein (CREB) and Activating Transcription Factor-1 (ATF-1) Is Modulated by Protein…
Transcription of the transforming growth factor-β2 (TGF-β2) gene is dependent on a cAMP-response element/activating transcription… 
1999
1999
Mitogen-activated protein kinase and protein kinase A signaling pathways stimulate cholecystokinin transcription via activation of cyclic adenosine 3',5'-monophosphate response element-binding…
Cholecystokinin (CCK) is a potent neuropeptide expressed in the small intestine and in the central nervous system. We have… 
Highly Cited
1997
Highly Cited
1997
Down-regulation of the Cyclin A Promoter by Transforming Growth Factor-β1 Is Associated with a Reduction in Phosphorylated Activating Transcription Factor-1 and Cyclic AMP-responsive Element-binding…
Transforming growth factor (TGF)-β1 prevents cell cycle progression by inhibiting several regulators, including cyclin A. To… 
1996
1996
c-fos CRE-binding activity of CREB/ATF family in the SCN is regulated by light but not a circadian clock
1995
1995
Activating transcription factor-1 is a specific antagonist of the cyclic adenosine 3'.5'-monophosphate (cAMP) response element-binding protein-1-mediated response to cAMP.
We have investigated the molecular basis of the variability of the somatostatin cAMP response element (CRE) function in different… 
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