Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

abarelix

Known as: N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-D-asparaginyl-L-leucyl-N(6)-(1-methylethyl)-L-lysyl-L-prolyl-D-alaninamide, abarelix [Chemical/Ingredient] 
A synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Hormonal therapy is the main recommended treatment for locally advanced and metastatic prostate cancer. Luteinizing hormone… Expand
Is this relevant?
Review
2006
Review
2006
Abarelix, a gonadotropin-releasing hormone antagonist, with its indication for advanced symptomatic prostate cancer, represents… Expand
Is this relevant?
Review
2004
Review
2004
GnRH agonists have a proven and well-established role in the management of prostate cancer. Further adaptations of the amino-acid… Expand
Is this relevant?
2003
2003
OBJECTIVES To evaluate the ability of abarelix, a gonadotropin-releasing hormone antagonist, to provide an alternative treatment… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
PURPOSE We compared the endocrinological and biochemical efficacy of abarelix depot, a gonadotropin-releasing hormone antagonist… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
We describe the pharmacological profile in rats and monkeys of degarelix (FE200486), a member of a new class of long-acting… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
OBJECTIVES To evaluate the levels of testosterone and other hormones in men with prostate cancer treated with abarelix versus… Expand
Is this relevant?
2001
2001
PURPOSE We contrasted the endocrinological and biochemical efficacies of abarelix depot, a pure gonadotropin-releasing hormone… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
A series of antagonists of gonadotropin-releasing hormone (GnRH) of the general formula Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P… Expand
Is this relevant?
2000
2000
PURPOSE A Phase II clinical study contrasted the endocrinologic and biochemical efficacy of Abarelix Depot, a gonadotropin… Expand
Is this relevant?