abarelix

Known as: N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-N-methyl-L-tyrosyl-D-asparaginyl-L-leucyl-N(6)-(1-methylethyl)-L-lysyl-L-prolyl-D-alaninamide, abarelix [Chemical/Ingredient] 
A synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2016
051020002016

Papers overview

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2006
2006
PURPOSE Although prostate cancer specific mortality is decreasing, there is little effect on overall mortality in this population… (More)
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2004
2004
4578 Background: The electrocardiographic QT interval measures ventricular repolarization, and, if prolonged, may predispose to… (More)
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2004
2004
OBJECTIVES To determine the efficacy of the gonadotropin-releasing hormone antagonist abarelix in patients with androgen… (More)
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2003
2003
OBJECTIVES To evaluate the ability of abarelix, a gonadotropin-releasing hormone antagonist, to provide an alternative treatment… (More)
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2002
2002
PURPOSE We compared the endocrinological and biochemical efficacy of abarelix depot, a gonadotropin-releasing hormone antagonist… (More)
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2001
2001
OBJECTIVES To evaluate the levels of testosterone and other hormones in men with prostate cancer treated with abarelix versus… (More)
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2001
2001
PURPOSE We contrasted the endocrinological and biochemical efficacies of abarelix depot, a pure gonadotropin-releasing hormone… (More)
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2001
2001
A series of antagonists of gonadotropin-releasing hormone (GnRH) of the general formula Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P… (More)
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2000
2000
PURPOSE A Phase II clinical study contrasted the endocrinologic and biochemical efficacy of Abarelix Depot, a gonadotropin… (More)
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Review
2000
Review
2000
Abarelix (PPI-149) is a luteinizing hormone-releasing hormone (LHRH) receptor antagonist under development by Praecis, Amgen and… (More)
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