Zinc Finger Protein GLIS2
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Nephronophthisis (NPHP), the leading genetic cause of end-stage renal failure in children and young adults, is a group of… Expand Krüppel-like zinc finger proteins form one of the largest families of transcription factors. They function as key regulators of… Expand Chimeric transcription factors are a hallmark of human leukemia, but the molecular mechanisms by which they block differentiation… Expand BackgroundCBFA2T3-GLIS2 is a fusion gene found in 17% of non-Down syndrome acute megakaryoblastic leukemia (non-DS AMKL, FAB M7… Expand Enlargement of kidney tubules is a common feature of multiple cystic kidney diseases in humans and mice. However, while some of… Expand The transcription factor Gli-similar 3 (Glis3) plays a critical role in the generation of pancreatic ß cells and the regulation… Expand Hedgehog (Hh) is a core signaling pathway implicated in fundamental processes during embryonic kidney development. We previously… Expand To gain insight into the mechanism by which Gli‐similar 2 (Glis2) regulates transcription, we performed yeast‐two hybrid cDNA… Expand In this study, we describe the characterization of a gene encoding a novel Krüppel-like protein, named Glis2. Glis2 encodes a… Expand In this study, we describe the sequence and genomic structure of the human GLIS2 gene, encoding a new member of the Krüppel-like… Expand