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Zenarestat

National Institutes of Health

Papers overview

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Review
2016
Review
2016
Diabetes mellitus occurrence has been associated to the modification of the physiological levels of glucose and is often… 
Review
2007
Review
2007
BACKGROUND Polyneuropathy, a common complication of diabetes mellitus, causes pain and sensory and motor deficits in the limbs… 
Highly Cited
2004
Highly Cited
2004
OBJECTIVE The aim of this study was to report the baseline and natural progression of diabetic peripheral neuropathy over 12… 
2002
2002
The crystal structure of the complex of human recombinant aldose reductase (AR) with zenarestat, one of its potent inhibitors… 
2000
2000
We studied the effects of zenarestat, an aldose reductase inhibitor (ARI), on peripheral neuropathy in Zucker diabetic fatty (ZDF… 
Highly Cited
1999
Highly Cited
1999
Objective: To determine whether the aldose reductase inhibitor (ARI) zenarestat improves nerve conduction velocity (NCV) and… 
1994
1994
Abstract— Zenarestat, (3‐(4‐bromo‐2‐fluorobenzyl)‐7‐chloro‐2,4‐dioxo‐1,2,3,4‐tetrahydroquinazolin‐1‐y1) acetic acid, an aldose… 
1991
1991
1. Rat shows a marked sex difference in the excretion of 14C-zenarestat: only 1% of the dose was excreted in the urine of males…