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Zenarestat

National Institutes of Health

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FR 74366

Papers overview

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2014
2014
Diabetic neuropathy--it's been a long journey: will we ever arrive?
2011
2011
Induced fit binding of aldose reductase inhibitors to AKR1B10
AKR1B10 is a recently identified NADP+ dependent aldo–keto reductase. It is strongly over expressed in lung and hepatic… 
Review
2002
Review
2002
Zenarestat. FK 366, FR 74366, FR 901366.
2001
2001
The effects of zenarestat, an aldose reductase inhibitor, on minimal F-wave latency and nerve blood flow in streptozotocin-induced diabetic rats.
2000
2000
Inhibitory effects of fidarestat on aldose reductase and aldehyde reductase activity evaluated by a new method using HPLC with post-column spectrophotometric detection.
A new method to assay the activity of aldose reductase (AR) and aldehyde reductase (AHR) by high-performance liquid… 
1999
1999
Continuous inhibition of excessive polyol pathway flux in peripheral nerves by aldose reductase inhibitor fidarestat leads to improvement of diabetic neuropathy.
1998
1998
Effect of SG-210, a novel aldose reductase inhibitor, on impaired polyol pathway in rats received diabetic manipulations.
1997
1997
Cataract development induced by repeated oral dosing with FK506 (tacrolimus) in adult rats.
1992
1992
Absorption, distribution and excretion of zenarestat, a new aldose reductase inhibitor, in rats and dogs.
1. The absorption, distribution and excretion of zenarestat have been studied in male rats and dogs after i.v. and oral… 
1992
1992
Effects of hypophysectomy and testosterone treatment on the urinary excretion of zenarestat in rats.
1. The effects of hypophysectomy and androgen treatment on the urinary excretion of zenarestat were investigated in Sprague… 
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