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Zankiren

Known as: (S)-N-((1S,2R,3S)-1-(Cyclohexylmethyl)-2,3-Dihydroxy-5-Methylhexyl)-Alpha((Alpha-S)-Alpha(((4-Methyl-1-Piperazinyl)Sulfonyl)Methyl)Hydrocinnamamido)-4-Thiazolepropionamide, 4-Thiazolepropanamide, N-(1-(Cyclohexylmethyl)-2,3-Dihydroxy-5-Methylhexyl)-Alpha-((2-(((4-Methyl-1-Piperazinyl)Sulfonyl)Methyl)-1-Oxo-3-Phenylpropyl)Amino)-, (1S-(1R*,(R*(R*)),2S*,3R*))- 
 
National Institutes of Health

Papers overview

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2015
2015
We investigate the binding mechanism in renin complexes, involving three drugs (remikiren, zankiren and enalkiren) and one lead… Expand
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Review
2012
Review
2012
Standard treatments available today for treating hypertension is diuretics, β-blockers, angiotensin converting enzyme inhibitors… Expand
Highly Cited
2005
Highly Cited
2005
Objectives Aliskiren is a new renin inhibitor of a novel structural class that has recently been shown to be efficacious in… Expand
1995
1995
BACKGROUND Zankiren HCl (A-72517) is a potent renin inhibitor shown to have substantial bioavailability in several animal species… Expand
1995
1995
Renin inhibition represents an alternative to angiotensin‐converting enzyme (ACE) inhibition for pharmacologic interruption of… Expand