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ZJM 289

Known as: ZJM-289, ZJM289 
National Institutes of Health

Papers overview

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2014
2014
Pharmacokinetics in Sprague-Dawley rats and Beagle dogs and in vitro metabolism of ZJM-289, a novel nitric dioxide donor
Abstract 1. The aim was to evaluate the prodrug hypothesis by investigating the pharmacokinetics of ZJM-289 and its… 
2012
2012
Studies on the enantiomers of ZJM-289: synthesis and biological evaluation of antiplatelet, antithrombotic and neuroprotective activities.
ZJM-289 is a potent racemic agent which inhibits both platelet aggregation and thrombosis superior to a known anti-ischemic… 
2011
2011
Identification of circulatory and excretory metabolites of a novel nitric oxide donor ZJM-289 in rat plasma, bile, urine and faeces by liquid chromatography–tandem mass spectrometry
ZJM-289, [2-(1-diethylaminoacetoxy)pentyl] benzoic acid-{2-methoxy-4-[2-(4-nitrooxybutoxy carbonyl)-vinyl]}phenyl ester… 
2010
2010
ZJM‐289, a novel nitric oxide donor, alleviates the cerebral ischaemic–reperfusion injury in rats
1. Current studies indicate that nitric oxide (NO) plays a dual role as both a protective and pathogenic factor in focal cerebral… 
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