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Z-Endoxifen Hydrochloride

Known as: 4-Hydroxy-N-Desmethyltamoxifen Hydrochloride, Z-Endoxifen HCl 
The hydrochloride salt and the z (cis-) stereoisomer of endoxifen with potential antineoplastic activity. Endoxifen, the active metabolite of… Expand
National Institutes of Health

Papers overview

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2018
2018
Background: Curcumin was shown to reduce epithelial-mesenchymal transition (EMT) markers in previous short term studies. This… Expand
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2017
2017
Purpose Endoxifen is a tamoxifen metabolite with potent antiestrogenic activity. Patients and Methods We performed a phase I… Expand
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2017
2017
BackgroundControversies exist as to whether the genetic polymorphisms of the enzymes responsible for the metabolism of tamoxifen… Expand
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2017
2017
Background and ObjectivesA better understanding of the highly variable pharmacokinetics (PK) of tamoxifen and its active… Expand
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2017
2017
Background: Z-endoxifen (further referred to as endoxifen, unless stated otherwise) is proposed as the most important metabolite… Expand
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2016
2016
BackgroundZ-endoxifen is the most potent of the metabolites of tamoxifen, and has the potential to be more effective than… Expand
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2016
2016
A versatile and efficient modular synthetic platform was developed for assembling multifunctional conjugates and targeted forms… Expand
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2014
2014
BackgroundReduced CYP2D6 metabolism and low Z-endoxifen (ENDX) concentrations may increase the risk of breast cancer recurrence… Expand
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2014
2014
Although tamoxifen is a successful agent for treatment and prevention of estrogen-dependent breast cancer, its use has been… Expand
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2010
2010
AbstractA comprehensive method was developed for the simultaneous trace analysis of ten hormone antagonist pharmaceuticals… Expand
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