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YY1 Transcription Factor

Known as: Transcription Factor, YY1, Transcriptional Repressor Protein YY1, Delta Transcription Factor 
A ubiquitously expressed zinc finger-containing protein that acts both as a repressor and activator of transcription. It interacts with key… Expand
National Institutes of Health

Related topics

Related topics

16 relations
CYS2-HIS2 Zinc FingersIn BloodNF-E2 Transcription FactorProcess of secretion
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Broader (1)

Nuclear Proteins

Narrower (3)

Transcriptional Repressor Protein YY1, humanYY1 protein, XenopusYY1 transcription factor, rat

Papers overview

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Highly Cited
2015
Highly Cited
2015
Transcription factor trapping by RNA in gene regulatory elements
Noncoding RNA helps protein binding Besides reading the coding regions of genes, RNA polymerase generates RNA at promoter… Expand
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Highly Cited
2015
Highly Cited
2015
Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1.
Little is known how lincRNAs are involved in skeletal myogenesis. Here we describe the discovery of Linc-YY1 from the promoter of… Expand
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Highly Cited
2013
Highly Cited
2013
microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis
Using microRNA (miRNA) expression array, we identified that miR-7 was deregulated in colorectal cancer (CRC). We studied the… Expand
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Highly Cited
2010
Highly Cited
2010
The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression
ABSTRACT The candidate tumor suppressor BAP1 is a deubiquitinating enzyme (DUB) involved in the regulation of cell proliferation… Expand
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Highly Cited
2009
Highly Cited
2009
Regulation of the transcription factor YY1 in mitosis through phosphorylation of its DNA-binding domain.
Yin-Yang 1 (YY1) is a ubiquitously expressed zinc finger transcription factor. It regulates a vast array of genes playing… Expand
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Highly Cited
2007
Highly Cited
2007
mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
Transcriptional complexes that contain peroxisome-proliferator-activated receptor coactivator (PGC)-1α control mitochondrial… Expand
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Highly Cited
2007
Highly Cited
2007
YY1 functions with INO80 to activate transcription
Ubiquitously expressed transcription factor Yin-Yang-1 (YY1) controls expression of many genes. YY1 is tightly associated with… Expand
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Review
2006
Review
2006
Transcription factor YY1: structure, function, and therapeutic implications in cancer biology
The ubiquitous transcription factor Yin Yang 1 (YY1) is known to have a fundamental role in normal biologic processes such as… Expand
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Highly Cited
2004
Highly Cited
2004
YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress.
The tumor suppressor p53 regulates cell-cycle progression and apoptosis in response to genotoxic stress, and inactivation of p53… Expand
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Highly Cited
2004
Highly Cited
2004
Yin Yang 1 Is a Negative Regulator of p53
Yin Yang 1 (YY1) is a transcription factor that plays an essential role in development. However, the full spectrum of YY1's… Expand
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