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YY1 Transcription Factor

Known as: Transcription Factor, YY1, Transcriptional Repressor Protein YY1, Delta Transcription Factor 
A ubiquitously expressed zinc finger-containing protein that acts both as a repressor and activator of transcription. It interacts with key… 
National Institutes of Health

Related topics

Related topics

16 relations
CYS2-HIS2 Zinc FingersIn BloodNF-E2 Transcription FactorProcess of secretion

Broader (1)

Nuclear Proteins

Narrower (3)

Transcriptional Repressor Protein YY1, humanYY1 protein, XenopusYY1 transcription factor, rat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Histone deacetylase inhibitors suppress mutant p53 transcription via HDAC8/YY1 signals in triple negative breast cancer cells.
Highly Cited
2010
Highly Cited
2010
The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression
ABSTRACT The candidate tumor suppressor BAP1 is a deubiquitinating enzyme (DUB) involved in the regulation of cell proliferation… 
Highly Cited
2009
Highly Cited
2009
PTEN suppression of YY1 induces HIF-2 activity in von hippel lindau null renal cell carcinoma
We are grateful to the following for their generous gifts: Dr. William G. Kaelin, Jr. for use of the WT8 and pRc-9 cells and the… 
Highly Cited
2008
Highly Cited
2008
The combined immunodetection of AP-2α and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors
IntroductionOverexpression of the ERBB2 oncogene is observed in about 20% of human breast tumors and is the consequence of… 
Highly Cited
2008
Highly Cited
2008
Inhibition of Yin Yang 1-Dependent Repressor Activity of DR5 Transcription and Expression by the Novel Proteasome Inhibitor NPI-0052 Contributes to its TRAIL-Enhanced Apoptosis in Cancer Cells1
TRAIL promotes apoptotic tumor cell death; however, TRAIL-resistant tumors need to be sensitized to reverse resistance… 
Review
2008
Review
2008
The Yin and Yang of YY1 in the nervous system
The transcription factor Yin Yang 1 (YY1) is a multifunctional protein that can activate or repress gene expression depending on… 
Highly Cited
2008
Highly Cited
2008
Loss of p53 induces epidermal growth factor receptor promoter activity in normal human keratinocytes
Overexpression of the epidermal growth factor receptor (EGFR) in human papillomavirus type 16-immortalized human keratinocytes… 
Review
2007
Review
2007
‘Rituximab-induced inhibition of antiapoptotic cell survival pathways: implications in chemo/immunoresistance, rituximab unresponsiveness, prognostic and novel therapeutic interventions’
Rituximab (chimeric anti-CD20 monoclonal antibody) is the first Food and Drug Administration approved antitumor antibody and is… 
Highly Cited
2003
Highly Cited
2003
The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene interfering with neutrophilic differentiation.
The genetic defects underlying the pathogenesis of acute myeloid leukemia (AML) are still largely unknown. Retroviral insertion… 
Highly Cited
1997
Highly Cited
1997
Interaction of the transcription factor YY1 with human poly(ADP-ribosyl) transferase.
Poly(ADP-ribosyl) transferase (ADPRT) is a nuclear enzyme that catalyzes the synthesis of ADP-ribose polymers from NAD+ as well… 
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