YOD1 gene

Ubiquitination, a fundamental post-translational modification of intracellular proteins, is enzymatically reversed by… Expand

Hippo signaling pathway is considered a key regulator of tissue homeostasis, cell proliferation, apoptosis and it is involved in… Expand

Diminished mitochondrial function impacts on cellular metabolism but also critically influences life and also health span… Expand

Significance The Hippo pathway restricts cell proliferation and plays key roles in organ size control and tissue homeostasis. The… Expand

The ubiquitin ligase TRAF6 is a key regulator of canonical IκB kinase (IKK)/NF-κB signaling in response to interleukin-1 (IL-1… Expand

Advances in the understanding of the Hippo signaling as a key regulatory pathway of proliferation and apoptosis have provided… Expand

Background: The AAA-ATPase VCP/p97 and the deubiquitinase YOD1 are required in the endoplasmic reticulum-associated degradation… Expand