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YM 928

Known as: YM-928, YM928, YM928 cpd 
National Institutes of Health

Papers overview

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2019
2019
Synthesis and Pharmacological Evaluation of 3-[(4-Oxo-4H-pyrido[3,2-e][1,3]thiazin-2-yl)(phenyl)amino]propanenitrile Derivatives as Orally Active AMPA Receptor Antagonists.
In our search for novel orally active α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists, we found… 
2006
2006
Simultaneous determination of YM928, a novel noncompetitive AMPA receptor antagonist, and its demethylated metabolite in rat, dog and monkey plasma by high-performance liquid chromatography with…
A specific HPLC method for the simultaneous determination of YM928, a novel noncompetitive AMPA receptor antagonist, and its… 
2004
2004
Effects of 2-[N-(4-Chlorophenyl)-N-methylamino]-4H-pyrido[3.2-e]-1,3-thiazin-4-one (YM928), an Orally Active α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor Antagonist, in Models of…
The anticonvulsant activity of 2-[N-(4-chlorophenyl)-N-methylamino]-4H-pyrido[3.2-e]-1,3-thiazin-4-one (YM928), a novel α-amino-3… 
2004
2004
Effect of YM928, a novel AMPA receptor antagonist, on seizures in EL mice and kainate-induced seizures in rats
Kainate-induced seizures and seizures induced by tossing stimulation in epilepsy-prone EL mice are considered as models of… 
2004
2004
Pharmacological studies of a novel AMPA receptor antagonist, YM928
2003
2003
Functional Characterization of YM928, a Novel Noncompetitive AMPA Receptor Antagonist
Co p y r ight 20 0 3 by t he Am er ican So ciet y fo r Phar m aco lo gy an d Ex p er im en t al Ther ap eu t ics . 
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