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YM 298198

Known as: YM-298198, YM298198 
National Institutes of Health

Papers overview

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2017
2017
Cardiac mGluR1 metabotropic receptors in cardioprotection.
Aims In a previous study using a genome-wide microarray strategy, we identified metabotropic glutamate receptor 1 (mGluR1) as a… 
2014
2014
Activation of lateral hypothalamic mGlu1 and mGlu5 receptors elicits feeding in rats
2011
2011
Examination of a role for metabotropic glutamate receptor 5 in the medial prefrontal cortex in cocaine sensitization in rats
RationaleGlutamatergic projection neurons in the medial prefrontal cortex (mPFC) are hyperexcitable in cocaine-sensitized animals… 
2010
2010
Evaluation of Cannabinoid Receptor 2 and Metabotropic Glutamate Receptor 1 Functional Responses Using a Cell Impedance–Based Technology
Recently, new technologies based on biosensors and called label free have been developed. These technologies eliminate the need… 
2010
2010
Pharmacological effects of metabotropic glutamate receptor ligands on prepulse inhibition in DBA/2J mice.
2009
2009
Identification of a novel transmembrane domain involved in the negative modulation of mGluR1 using a newly discovered allosteric mGluR1 antagonist, 3-cyclohexyl-5-fluoro-6-methyl-7-(2-morpholin-4…
2009
2009
Non-competitive metabotropic glutamate 1 receptor antagonists block activity of slowly adapting type I mechanoreceptor units in the rat sinus hair follicle
2007
2007
Potent and specific action of the mGlu1 antagonists YM‐298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices
Specific and selective inhibitors for mGlu1 receptors are presently inadequate. A new generation of non‐competitive mGlu1… 
Highly Cited
2007
Highly Cited
2007
Synthesis and preliminary biological evaluation of 3‐[18F]fluoro‐5‐(2‐pyridinylethynyl)benzonitrile as a PET radiotracer for imaging metabotropic glutamate receptor subtype 5
The metabotropic glutamate receptor subtype 5 (mGluR5) has been reported to be implicated in various neurological disorders in… 
Highly Cited
2005
Highly Cited
2005
Radioligand Binding Properties and Pharmacological Characterization of 6-Amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a High-Affinity, Selective, and…
Metabotropic glutamate receptor type 1 (mGluR1) is thought to play important roles in the neurotransmission and pathogenesis of… 
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