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YM 244769

Known as: YM-244769, YM244769 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2016
012320062016

Papers overview

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2017
2017
Chronic pharmacological blockade of the Na+ /Ca2+ exchanger modulates the growth and development of the Purkinje cell dendritic arbor in mouse cerebellar slice cultures.
The Na+ /Ca2+ exchanger (NCX) is a bidirectional plasma membrane antiporter involved in Ca2+ homeostasis in eukaryotes. NCX has… (More)
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2016
2016
Inhibitory effect of YM-244769, a novel Na+/Ca2+ exchanger inhibitor on Na+/Ca2+ exchange current in guinea pig cardiac ventricular myocytes
Recently, YM-244769 (N-(3-aminobenzyl)-6-{4-[(3-fluorobenzyl)oxy]phenoxy} nicotinamide) has been reported as a new potent and… (More)
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2015
2015
Reciprocal Regulation of Mitochondrial Dynamics and Calcium Signaling in Astrocyte Processes.
UNLABELLED We recently showed that inhibition of neuronal activity, glutamate uptake, or reversed-Na(+)/Ca(2+)-exchange with TTX… (More)
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2015
2015
Genetic knockout and pharmacologic inhibition of NCX2 cause natriuresis and hypercalciuria.
The Na(+)/Ca(2+) exchanger (NCX) is a bidirectional transporter that is controlled by membrane potential and transmembrane… (More)
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2014
2014
Ca2+ influx via the Na+/Ca2+ exchanger is enhanced in malignant hyperthermia skeletal muscle.
Malignant hyperthermia (MH) is potentially fatal pharmacogenetic disorder of skeletal muscle caused by intracellular Ca(2… (More)
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2014
2014
Cardiac P2X purinergic receptors as a new pathway for increasing Na⁺ entry in cardiac myocytes.
P2X4 receptors (P2X4Rs) are ligand-gated ion channels capable of conducting cations such as Na(+). Endogenous cardiac P2X4R can… (More)
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2012
2012
Na(+) /Ca(2+) exchanger 2-heterozygote knockout mice display decreased acetylcholine release and altered colonic motility in vivo.
BACKGROUND The Na(+) /Ca(2+) exchanger (NCX) is a plasma membrane transporter involved in regulating intracellular Ca(2… (More)
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2012
2012
Functional and morphological properties of pericytes in suburothelial venules of the mouse bladder.
BACKGROUND AND PURPOSE In suburothelial venules of rat bladder, pericytes (perivascular cells) develop spontaneous Ca(2… (More)
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2006
2006
YM-244769, a novel Na+/Ca2+ exchange inhibitor that preferentially inhibits NCX3, efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage.
We investigated the pharmacological properties and interaction domains of N-(3-aminobenzyl)-6-{4-[(3-fluorobenzyl)oxy]phenoxy… (More)
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2006
2006
YM-244769, a Novel Na /Ca Exchange Inhibitor That Preferentially Inhibits NCX3, Efficiently Protects against Hypoxia/Reoxygenation-Induced SH-SY5Y Neuronal Cell Damage
We investigated the pharmacological properties and interaction domains of N-(3-aminobenzyl)-6-{4-[(3-fluorobenzyl)oxy]phenoxy… (More)
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