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YM 060

Known as: YM-060, YM060 
National Institutes of Health

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Broader (1)

ramosetron

Papers overview

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1998
1998
Inhibition of stress‐stimulated colonic propulsion by α2‐adrenoceptor antagonists in rats
Alpha2‐adrenoceptor antagonists have been reported to stimulate colonic motor activity, but the effect on colonic motor… 
1997
1997
Effect of ramosetron on short-circuit current response in rat colonic mucosa.
1996
1996
Characterization of 5-hydroxytryptamine (5-HT) receptor subtypes influencing colonic motility in conscious dogs
We examined the effects of exogenous 5-hydroxytryptamine (5-HT) and selective 5-HT receptor agonists and antagonists on proximal… 
1996
1996
Investigation of 5-HT3 receptor-mediated contraction in guinea-pig distal colon.
1996
1996
Novel 5-hydroxytryptamine (5-HT3) receptor antagonists. III. Pharmacological evaluations and molecular modeling studies of optically active 4,5,6,7-tetrahydro-1H-benzimidazole derivatives.
The R- and S-enantiomers of the 4,5,6,7-tetrahydro-1H-benzimidazole derivatives 3-8 were prepared by optical resolution. Each R… 
1995
1995
Studies on serotonin (5-HT)3-receptor antagonist effects of enantiomers of 4,5,6,7-tetrahydro-1H-benzimidazole derivatives.
We assessed the 5-HT3-receptor antagonist effects of 4,5,6,7-1H-benzimidazole compounds which are derivatives of YM060, a potent… 
1995
1995
Species difference in the 5-hydroxytryptamine3 receptor associated with the von Bezold-Jarisch reflex.
Species differences in the 5-hydroxytryptamine (5-HT)3 receptor among anesthetized rats, mice, rabbits, ferrets, dogs and guinea… 
Highly Cited
1993
Highly Cited
1993
Mechanisms of cisplatin- and m-chlorophenylbiguanide-induced emesis in ferrets.
1993
1993
5-HT3 receptor antagonists. 3. Quinoline derivatives which may be effective in the therapy of irritable bowel syndrome.
A series of quinolinecarboxylic acid derivatives has been previously described as a new class of 5-HT3 receptor antagonists due… 
1991
1991
Antiemetic effects of YM060, a potent and selective serotonin (5HT)3-receptor antagonist, in ferrets and dogs.
YM060, (R)-5-[(1-methyl-3-indolyl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole hydrochloride, is a new serotonin (5HT)3-receptor… 
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