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YH 439
Known as:
YH-439
, YH439
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Thiazoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Nucleotide specificity of DNA binding of the aryl hydrocarbon receptor:ARNT complex is unaffected by ligand structure.
D. DeGroot
,
M. Denison
Toxicological sciences : an official journal of…
2014
Corpus ID: 18708662
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxic and biological effects of…
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2010
2010
Amino Acid Substitutions in the Aryl Hydrocarbon Receptor Ligand Binding Domain Reveal YH439 As an Atypical AhR Activator
F. Whelan
,
Nan Hao
,
S. Furness
,
M. Whitelaw
,
A. Chapman-Smith
Molecular Pharmacology
2010
Corpus ID: 18142399
The aryl hydrocarbon receptor (AhR) is traditionally defined as a transcription factor activated by exogenous polyaromatic and…
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2010
2010
Thermal reversible microemulsion system for poorly water-soluble YH439 for oral delivery.
D. Han
,
Zhe-Hu Jin
,
Yan Jin
,
Xue-zhe Yin
,
Yuanyuan Shen
,
Zhong-gao Gao
Chemical & pharmaceutical bulletin
2010
Corpus ID: 29275977
To improve bioavailability of poorly water-soluble YH439, a thermal reversible microemulsion system was prepared using modified…
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Highly Cited
2001
Highly Cited
2001
Acetaminophen induces apoptosis of C6 glioma cells by activating the c-Jun NH(2)-terminal protein kinase-related cell death pathway.
M. Bae
,
J. Pié
,
B. Song
Molecular pharmacology
2001
Corpus ID: 22032446
Acetaminophen (AAP), a widely used analgesic drug, can damage various organs when taken in large doses. In this study, we…
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2000
2000
Cytochrome P450 2E1 (CYP2E1)-dependent production of a 37-kDa acetaldehyde-protein adduct in the rat liver.
K. Jeong
,
Y. Soh
,
J. Jeng
,
M. Felder
,
J. Hardwick
,
B. Song
Archives of biochemistry and biophysics
2000
Corpus ID: 37445937
Ethanol-inducible cytochrome P450 2E1 (CYP2E1) has been shown to be involved in the metabolism of both ethanol and acetaldehyde…
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1999
1999
Inhibitory effects of isopropyl-2-(1,3-dithietane-2-ylidene)-2- [N-(4-methylthiazol-2-yl)carbamoyl]acetate (YH439) on benzo[a]pyrene-induced skin carcinogenesis and micronucleated reticulocyte…
Y. Surh
,
S. G. Kim
,
A. Liem
,
J. Lee
,
J. Miller
Mutation research
1999
Corpus ID: 24497559
1998
1998
Species differences in pharmacokinetics of a hepatoprotective agent, YH439, and its metabolites, M4, M5, and M7, after intravenous and oral administration to rats, rabbits, and dogs.
W. Yoon
,
J. Yoo
,
J. Lee
,
C. Shim
,
M. Lee
Drug metabolism and disposition: the biological…
1998
Corpus ID: 1107580
Pharmacokinetic parameters of YH439 and its metabolites, M4, M5, and M7, were compared after iv administration of YH439 to rats…
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1996
1996
Transcriptional induction of the cytochrome P4501A1 gene by a thiazolium compound, YH439.
I. J. Lee
,
K. Jeong
,
+4 authors
B. Song
Molecular pharmacology
1996
Corpus ID: 22586131
The molecular mechanism of induction of cytochromes P4501A1/2 (CYP1A1/2) by a synthetic compound YH439 was studied in rodents as…
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1996
1996
Transcriptional inhibition of cytochrome P4502E1 by a synthetic compound, YH439.
K. Jeong
,
I. J. Lee
,
+4 authors
B. Song
Archives of biochemistry and biophysics
1996
Corpus ID: 25772794
The molecular mechanism of cytochrome P4502E1 (CYP2E1) inhibition by a synthetic compound, YH439, was studied. In rats treated…
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1996
1996
Inhibition of covalent DNA binding and mutagenicity of benzo[a]pyrene by isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2-yl) carbamoyl]acetate (YH439), a novel hepatoprotective agent.
Y. Surh
,
M. Shlyankevich
,
J. Lee
,
J. Yoo
Mutation research
1996
Corpus ID: 32519571
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