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YH 439

Known as: YH-439, YH439 
 
National Institutes of Health

Papers overview

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2014
2014
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxic and biological effects of… Expand
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2010
2010
To improve bioavailability of poorly water-soluble YH439, a thermal reversible microemulsion system was prepared using modified… Expand
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2010
2010
The aryl hydrocarbon receptor (AhR) is traditionally defined as a transcription factor activated by exogenous polyaromatic and… Expand
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Highly Cited
2001
Highly Cited
2001
Acetaminophen (AAP), a widely used analgesic drug, can damage various organs when taken in large doses. In this study, we… Expand
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2000
2000
Ethanol-inducible cytochrome P450 2E1 (CYP2E1) has been shown to be involved in the metabolism of both ethanol and acetaldehyde… Expand
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1999
1999
Recently, a great deal of attention has been devoted to organosulfur compounds with potential cancer chemopreventive properties… Expand
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1998
1998
Pharmacokinetic parameters of YH439 and its metabolites, M4, M5, and M7, were compared after iv administration of YH439 to rats… Expand
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1998
1998
First-pass effects of YH439 were evaluated after intravenous, intraportal, oral, and intraduodenal administration of the drug… Expand
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1996
1996
The molecular mechanism of induction of cytochromes P4501A1/2 (CYP1A1/2) by a synthetic compound YH439 was studied in rodents as… Expand
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1996
1996
The molecular mechanism of cytochrome P4502E1 (CYP2E1) inhibition by a synthetic compound, YH439, was studied. In rats treated… Expand
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