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YAC-Based STS-Content Mapping

YAC based content mapping is a clone-based physical genome mapping strategy. Content mapping is done by ordering sequence tagged sites (STS), regions… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Conservation of aphidicolin-induced fragile sites in Papionini (Primates) species and humans
Fragile sites are considered structural features of mammalian chromosomes and a commonly repeated hypothesis is that they are… 
Highly Cited
2003
Highly Cited
2003
Sequence and structure of the extrachromosomal palindrome encoding the ribosomal RNA genes in Dictyostelium.
Ribosomal RNAs (rRNAs) are encoded by multicopy families of identical genes. In Dictyostelium and other protists, the rDNA is… 
Review
2001
Review
2001
Size Matters: Use of YACs, BACs and PACs in Transgenic Animals
In 1993, several groups, working independently, reported the successful generation of transgenic mice with yeast artificial… 
Highly Cited
1999
Highly Cited
1999
Incidence and clinical significance of 6q deletions in B cell chronic lymphocytic leukemia
Deletions affecting the long arm of chromosome 6 (6q) are among the most commonly observed chromosomal aberrations in lymphoid… 
Review
1997
Review
1997
Physical mapping of the rice genome with YAC clones
Construction of a rice physical map covered by YAC clones which have been arranged over half of the genome length is presented… 
Review
1995
Review
1995
The CIC library: a large insert YAC library for genome mapping in Arabidopsis thaliana.
A new Arabidopsis thaliana (ecotype Columbia) genomic library has been constructed in Yeast Artificial Chromosomes: the CIC… 
Highly Cited
1995
Highly Cited
1995
An integrated physical and genetic map of a 35 Mb region on chromosome Xp22.3-Xp21.3.
We have constructed a detailed physical map of the 35 Mb region spanning human chromosome Xp22.3-Xp21.3. The backbone of the map… 
1992
1992
Cloning of the Huntington disease region in yeast artificial chromosomes.
The gene responsible for Huntington disease has been localized to a 2.5 million base pair (Mb) region between the loci D4S10 and… 
Review
1991
Review
1991
Sequence-tagged site (STS) content mapping of human chromosomes: theoretical considerations and early experiences.
The magnitude of the effort required to complete the human genome project will require constant refinements of the tools… 
1991
1991
Construction and characterization of a yeast artificial chromosome library of Arabidopsis which is suitable for chromosome walking
SummaryA yeast artificial chromosome (YAC) genomic library of Arabidopsis thaliana was constructed in a derivative of the vector… 
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