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XV 454

Known as: XV-454, XV454 
National Institutes of Health

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3 relations

Broader (2)

AlanineOxazoles
analogs & derivatives

Papers overview

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1998
1998
XV454, a novel nonpeptide small-molecule platelet GIIb/IIIa antagonist with comparable platelet alpha(IIb)beta3-binding kinetics to c7E3.
XV454 demonstrated high potency (IC50 = 14-25 nM) in inhibiting human platelet aggregation induced by adenosine diphosphate (ADP… 
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