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Whole-Brain Radiotherapy

Known as: WBRT, whole-brain radiation therapy 
A type of external radiation therapy used to treat patients who have cancer in the brain. It is often used to treat patients whose cancer has spread… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Pan-Asian adapted Clinical Practice Guidelines for the management of patients with metastatic non-small-cell lung cancer: a CSCO–ESMO initiative endorsed by JSMO, KSMO, MOS, SSO and TOS
The most recent version of the European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis… Expand
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Highly Cited
2014
Highly Cited
2014
Preservation of memory with conformal avoidance of the hippocampal neural stem-cell compartment during whole-brain radiotherapy for brain metastases (RTOG 0933): a phase II multi-institutional trial.
PURPOSE Hippocampal neural stem-cell injury during whole-brain radiotherapy (WBRT) may play a role in memory decline. Intensity… Expand
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial.
BACKGROUND To determine the protective effects of memantine on cognitive function in patients receiving whole-brain radiotherapy… Expand
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Review
2012
Review
2012
Primary brain tumours in adults
Important advances have been made in the understanding and management of adult gliomas and primary CNS lymphomas--the two most… Expand
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Highly Cited
2011
Highly Cited
2011
Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study.
PURPOSE This European Organisation for Research and Treatment of Cancer phase III trial assesses whether adjuvant whole-brain… Expand
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Highly Cited
2009
Highly Cited
2009
Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial.
BACKGROUND It is unclear whether the benefit of adding whole-brain radiation therapy (WBRT) to stereotactic radiosurgery (SRS… Expand
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Highly Cited
2006
Highly Cited
2006
Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial.
CONTEXT In patients with brain metastases, it is unclear whether adding up-front whole-brain radiation therapy (WBRT) to… Expand
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Highly Cited
2004
Highly Cited
2004
Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial
BACKGROUND Brain metastases occur in up to 40% of all patients with systemic cancer. We aimed to assess whether stereotactic… Expand
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Highly Cited
1999
Highly Cited
1999
Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases.
PURPOSE Multiple brain metastases are a common health problem, frequently diagnosed in patients with cancer. The prognosis, even… Expand
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Highly Cited
1998
Highly Cited
1998
Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial.
CONTEXT For the treatment of a single metastasis to the brain, surgical resection combined with postoperative radiotherapy is… Expand
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