Whole-Brain Radiotherapy

Known as: WBRT, whole-brain radiation therapy 
A type of external radiation therapy used to treat patients who have cancer in the brain. It is often used to treat patients whose cancer has spread… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial.
BACKGROUND To determine the protective effects of memantine on cognitive function in patients receiving whole-brain radiotherapy… (More)
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Highly Cited
2009
Highly Cited
2009
Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial.
BACKGROUND It is unclear whether the benefit of adding whole-brain radiation therapy (WBRT) to stereotactic radiosurgery (SRS… (More)
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Highly Cited
2008
Highly Cited
2008
Relationship between neurocognitive function and quality of life after whole-brain radiotherapy in patients with brain metastasis.
PURPOSE To examine the relationship between neurocognitive function (NCF) and quality of life (QOL) in patients with brain… (More)
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Highly Cited
2008
Highly Cited
2008
Memory function before and after whole brain radiotherapy in patients with and without brain metastases.
PURPOSE To prospectively compare the effect of prophylactic and therapeutic whole brain radiotherapy (WBRT) on memory function in… (More)
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Highly Cited
2007
Highly Cited
2007
Combined immunochemotherapy with reduced whole-brain radiotherapy for newly diagnosed primary CNS lymphoma.
PURPOSE Our goals were to evaluate the safety of adding rituximab to methotrexate (MTX)-based chemotherapy for primary CNS… (More)
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Highly Cited
2006
Highly Cited
2006
Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial.
CONTEXT In patients with brain metastases, it is unclear whether adding up-front whole-brain radiation therapy (WBRT) to… (More)
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Highly Cited
2005
Highly Cited
2005
Temozolomide and concomitant whole brain radiotherapy in patients with brain metastases: a phase II randomized trial.
PURPOSE To evaluate the safety profile and efficacy of whole brain radiotherapy (WBRT) concomitantly with temozolomide (TMZ) in… (More)
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Highly Cited
2004
Highly Cited
2004
Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial
BACKGROUND Brain metastases occur in up to 40% of all patients with systemic cancer. We aimed to assess whether stereotactic… (More)
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Highly Cited
1999
Highly Cited
1999
Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases.
PURPOSE Multiple brain metastases are a common health problem, frequently diagnosed in patients with cancer. The prognosis, even… (More)
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Highly Cited
1998
Highly Cited
1998
Radiosurgery alone or in combination with whole-brain radiotherapy for brain metastases.
PURPOSE Evaluation of the treatment outcome after radiosurgery (RS) alone or in combination with whole-brain radiotherapy (WBRT… (More)
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