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Weibel-Palade Bodies

Known as: Cytoplasmic vesicle of endothelial cell of artery, Bodies, Weibel-Palade, Weibel Palade Bodies 
A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally… 
National Institutes of Health

Related topics

Related topics

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Broader (1)

Cytoplasmic Vesicles
MicrobiologicalProcess of secretionaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2005
Highly Cited
2005
Re-establishment of VWF-dependent Weibel-Palade bodies in VWD endothelial cells.
Type 3 von Willebrand disease (VWD) is a severe hemorrhagic defect in humans. We now identify the homozygous mutation in the… 
Highly Cited
2003
Highly Cited
2003
Real-Time Imaging of the Dynamics and Secretory Behavior of Weibel-Palade Bodies
Objective—Weibel-Palade bodies (WPBs) are specialized secretory granules found in endothelial cells. These vesicles store… 
2001
2001
Inducible Nitric Oxide Synthase Inhibition of Weibel-Palade Body Release in Cardiac Transplant Rejection
Background—Inducible nitric oxide synthase (iNOS, or NOS2) reduces the severity of accelerated graft arteriosclerosis (AGA) in… 
Highly Cited
2000
Highly Cited
2000
The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells.
In the present study, we show that in human endothelial cells the tetraspanin CD63/lamp3 distributes predominantly to the… 
Highly Cited
1993
Highly Cited
1993
CD63 is a component of Weibel-Palade bodies of human endothelial cells.
Weibel-Palade bodies are secretory granules of vascular endothelial cells specialized in the storage of von Willebrand factor… 
Highly Cited
1991
Highly Cited
1991
Heterogeneous distribution of Weibel-Palade bodies and von Willebrand factor along the porcine vascular tree.
Vessels obtained from different levels of pig vascular tree were examined by transmission electron microscope, with the aim of… 
Highly Cited
1990
Highly Cited
1990
Endothelium specific Weibel-Palade bodies in a continuous human cell line, EA.hy926
SummaryWeibel-Palade bodies are ultrastructurally defined organelles found only in vascular endothelial cells. Because… 
Highly Cited
1987
Highly Cited
1987
Composition of the von Willebrand factor storage organelle (Weibel- Palade body) isolated from cultured human umbilical vein endothelial cells
von Willebrand factor (VWF) is a large, adhesive glycoprotein that is biosynthesized and secreted by cultured endothelial cells… 
Highly Cited
1984
Highly Cited
1984
Biosynthesis of von Willebrand protein by human endothelial cells: processing steps and their intracellular localization
Biosynthesis of von Willebrand protein by human umbilical vein endothelial cells involved distinct processing steps marked by the… 
Highly Cited
1977
Highly Cited
1977
Immunocytochemical localization of secretory proteins in bovine pancreatic exocrine cells
The bovine exocrine pancreatic cell produces a variety of enzymes and proenzymes for export. Biochemical studies by Greene L.J… 
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