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WZB117

National Institutes of Health

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1 relation

Broader (1)

Hydroxybenzoates

Papers overview

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2018
2018
Abstract 2799: New-generation glucose transporter inhibitors targeting non-small cell lung cancer and triple-negative breast cancer
Cancer is a top killer second only to cardiovascular diseases. Cellular metabolic reprogramming and altered energetics are key… 
2017
2017
Abstract 1157: Screening and identification of new generation glucose transporter inhibitors as anticancer therapeutics
Cancer is a top killer second only to cardiovascular diseases. Cellular metabolic reprogramming and altered energetics are key… 
2016
2016
Explorer A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models
  • 2016
  • Corpus ID: 264704413
Many cancer cells rely on aerobic glycolysis for energy production and targeting of this pathway is a potential strategy to… 
Highly Cited
2014
Highly Cited
2014
Overcoming 5-Fu resistance of colon cells through inhibition of Glut1 by the specific inhibitor WZB117.
BACKGROUND 5-Fluorouracil (5-FU) is the most commonly used drug in colon cancer therapy. However, despite impressive clinical… 
2012
2012
Therapeutic Discovery A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis , Induces Cell-Cycle Arrest , and Inhibits Cancer Cell Growth In Vitro and In Vivo
The functional and therapeutic importance of the Warburg effect is increasingly recognized, and glycolysis has become a target of… 
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