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WK175

Known as: WK 175 
 
National Institutes of Health

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Organic Chemicals

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2010
2010
A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity
Many types of malignant cells have a higher nicotinamide adenine dinucleotide (NAD) turnover rate than normal cells, as well as… Expand
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Highly Cited
2002
Highly Cited
2002
WK175, a novel antitumor agent, decreases the intracellular nicotinamide adenine dinucleotide concentration and induces the apoptotic cascade in human leukemia cells.
We recently developed a class of novel antitumor agents that elicit a potent growth-inhibitory response in many tumor cells… Expand
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