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WIPI2 gene

Known as: CGI-50, WD repeat domain, phosphoinositide interacting 2, DKFZP434J154 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation
ABSTRACT Macroautophagy/autophagy is a cellular process in which cytosolic contents are degraded by lysosome in response to… 
2019
2019
MTORC1 regulates autophagic membrane growth by targeting WIPI2
ABSTRACT WIPI2 contributes to autophagy by recruiting the ATG12–ATG5-ATG16L1 complex to PtdIns3P-rich membranes, which enables… 
2018
2018
Deficient autophagy and aging in Hydra 1 D eficient autophagy drives aging in Hydra
Hydra exhibits a negligible senescence as its epithelial and interstitial stem cell populations continuously divide. Here we… 
2016
2016
Atg8 lipidation is coordinated in a PtdIns3P-dependent manner by the PROPPIN Atg21
ABSTRACT In Saccharomyces cerevisiae Atg8 coupled to phosphatidylethanolamine is a key component of autophagosome biogenesis… 
2014
2014
Investigation of the role of WIPI2 in autophagosome formation : functional characterisation of the WIPI2-Atg16L1 interaction
Macroautophagy, here called autophagy, is a catabolic process that is required for cell homeostasis and cell survival under… 
2013
2013
Insights into membrane binding of PROPPINs and reconstitution of the mammalian autophagic conjugation systems.
Autophagy is a degradation pathway conserved in eukaryotes. Upon induction of autophagy a double layered membrane is formed de… 
Highly Cited
2010
Highly Cited
2010
Roles of the Lipid-binding Motifs of Atg18 and Atg21 in the Cytoplasm to Vacuole Targeting Pathway and Autophagy*
Atg18 and Atg21 are homologous WD-40 repeat proteins that bind phosphoinositides via a novel conserved Phe-Arg-Arg-Gly motif and… 
Highly Cited
2008
Highly Cited
2008
Dissecting the localization and function of Atg18, Atg21 and Ygr223c
Atg18p and Atg21p are two highly homologous yeast autophagy proteins. Atg18p functions in both autophagy and the selective Cvt… 
2007
2007
Creating a temperature sensitive mutant of Atg21 using intein [abstract]
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