WIPI2 gene

Mammalian cells deploy autophagy to defend their cytosol against bacterial invaders. Anti-bacterial autophagy relies on the core… (More)

In Saccharomyces cerevisiae Atg8 coupled to phosphatidylethanolamine is a key component of autophagosome biogenesis. Atg21 binds… (More)

Autophagosome formation is stimulated by canonical VPS34-dependent formation of phosphatidylinositol 3-phosphate [PI(3)P], which… (More)

Central to the process of macroautophagy (hereafter autophagy) is the formation of autophagosomes, double-membrane vesicles that… (More)

Macroautophagy, commonly referred to as autophagy, is a protein degradation pathway that occurs constitutively in cells, but can… (More)

The monocyte/macrophage is critical for regulating immune and antitumor responses. Recombinant capsid protein VP1 (rVP1) of foot… (More)

Autophagy is a catabolic process essential for cell homeostasis, at the core of which is the formation of double-membrane… (More)

Autophagosome formation is a complex process that begins with the nucleation of a pre-autophagosomal structure (PAS) that expands… (More)

Autophagy is a highly conserved pathway for the degradation and recycling of long-lived proteins and cytoplasmic organelles… (More)

ATG genes are required for autophagy-related processes that transport proteins/organelles destined for proteolytic degradation to… (More)