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WIN 53338

Known as: Isoxazole, 5-(5-(2-chloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)pentyl)-3-methyl-, WIN-53338, WIN53338 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Oxazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Allylic–Allylic Alkylation with 3,5-Dimethyl-4-nitroisoxazole: A Route to Dicarboxylic Acid Derivatives
In this work, the first application of 3,5-dimethyl-4-nitroisoxazole as a vinylogous pronucleophile in the allylic–allylic… 
2015
2015
Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP…
Exchange proteins directly activated by cAMP (EPAC) as guanine nucleotide exchange factors mediate the effects of the pivotal… 
2013
2013
Isoxazole norcantharidin derivative, and preparation method and application thereof
The invention discloses an isoxazole norcantharidin derivative, and a preparation method and an application thereof. The… 
2012
2012
Synthesis and Biological Evaluation of Novel N-phenyl-5-carboxamidyl Isoxazoles as Potential Chemotherapeutic Agents for Colon Cancer.
A new series of isoxazole derivatives, N-phenyl-5-carboxamidyl isoxazoles, was investigated for their anticancer activity with… 
2006
2006
3,4,5-Trisubstituted isoxazoles as novel PPARdelta agonists. Part 2.
1998
1998
The synthesis of new adenosine A3 selective ligands containing bioisosteric isoxazoles.
1998
1998
Dissociated dopaminergic neurons from substantia nigra zona compacta in young rats lack functional NMDA receptors
Abstract Glutamate-mediated excitotoxicity plays an important role in the degeneration of nigrostriatal dopamine (DA) neurons… 
1995
1995
Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties.
Compounds that activate neuronal nicotinic acetylcholine receptors (nAChRs) may have potential benefit in the treatment of… 
1993
1993
Effects of the antiviral WIN 54954 and the immune modulator LS 2616 on cachectin/TNF and gamma-interferon responses during viral heart disease.
The effects of the anti picornaviral drug WIN 54954 (5-(5-(2.6-dichloro-4-(4.5-dihydro-2-oxazolyl)phenoxy)pentyl)-3-me thyl… 
1966
1966
Effects of 5-Carboxy-3-Methylisoxazole on Carbohydrate and Fat Metabolism
Summary U-10387 (S-carboxy-3-methyl-isoxazole) was shown to increase glucose-1-C14 oxidation and depress release of FFA by… 
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