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WHAMM gene

Known as: KIAA1971, WHAMM1, WHDC1 
 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Cellular functions of WASP family proteins at a glance
ABSTRACT Proteins of the Wiskott–Aldrich syndrome protein (WASP) family function as nucleation-promoting factors for the… Expand
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2017
2017
An Amish founder mutation disrupts a PI(3)P-WHAMM-Arp2/3 complex–driven autophagosomal remodeling pathway
The actin assembly machinery coordinates a variety of membrane-remodeling processes. This paper shows that an inherited mutation… Expand
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Highly Cited
2015
Highly Cited
2015
WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism
Nucleation-promoting factors (NPFs) control the spatio-temporal activity of Arp2/3 complex in cells]. Thus, WASP and the WAVE… Expand
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2015
2015
WHAMM links actin assembly via the Arp2/3 complex to autophagy
Macroautophagy (hereafter autophagy) is the process by which cytosolic material destined for degradation is enclosed inside a… Expand
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2015
2015
Two-stage comprehensive evaluation of genetic susceptibility of common variants in FBXO38, AP3B2 and WHAMM to severe chronic periodontitis
Chronic periodontitis is an oral disorder characterized with gingival inflammation and bone destruction. As the sixth-most… Expand
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2012
2012
Structural insights into WHAMM-mediated cytoskeletal coordination during membrane remodeling
Structural analysis of the WHAMM–microtubule interaction provides insight into WHAMM’s coordination of microtubule binding… Expand
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2011
2011
Evolution of the eukaryotic ARP2/3 activators of the WASP family: WASP, WAVE, WASH, and WHAMM, and the proposed new family members WAWH and WAML
BackgroundWASP family proteins stimulate the actin-nucleating activity of the ARP2/3 complex. They include members of the well… Expand
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Review
2010
Review
2010
WASH, WHAMM and JMY: regulation of Arp2/3 complex and beyond.
Arp2/3 complex mediates the nucleation of actin filaments in multiple subcellular processes, and is activated by nucleation… Expand
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Review
2009
Review
2009
WASP and SCAR/WAVE proteins: the drivers of actin assembly
The actin cytoskeleton plays an essential role in numerous aspects of cell biology, such as cell morphology and motility. Actin's… Expand
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Highly Cited
2008
Highly Cited
2008
WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport
The Arp2/3 complex is an actin nucleator that plays a critical role in many cellular processes. Its activities are regulated by… Expand
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