WHAMM gene

ABSTRACT Proteins of the Wiskott–Aldrich syndrome protein (WASP) family function as nucleation-promoting factors for the… Expand

Nucleation-promoting factors (NPFs) control the spatio-temporal activity of Arp2/3 complex in cells]. Thus, WASP and the WAVE… Expand

RhoD is a member of the Rho GTPase family and it coordinates actin dynamics and membrane trafficking. Activation of RhoD results… Expand

Macroautophagy (hereafter autophagy) is the process by which cytosolic material destined for degradation is enclosed inside a… Expand

Junction-mediating and regulatory protein (JMY) was originally identified as a transcriptional co-factor in the p53-response to… Expand

Structural analysis of the WHAMM–microtubule interaction provides insight into WHAMM’s coordination of microtubule binding… Expand

BackgroundWASP family proteins stimulate the actin-nucleating activity of the ARP2/3 complex. They include members of the well… Expand

Arp2/3 complex mediates the nucleation of actin filaments in multiple subcellular processes, and is activated by nucleation… Expand

The actin cytoskeleton plays an essential role in numerous aspects of cell biology, such as cell morphology and motility. Actin's… Expand

The Arp2/3 complex is an actin nucleator that plays a critical role in many cellular processes. Its activities are regulated by… Expand