WHAMM gene

WASP homolog associated with actin, membranes, and microtubules (WHAMM) is a vertebrate protein functioning in membrane… (More)

Nucleation-promoting factors (NPFs) control the spatio-temporal activity of Arp2/3 complex in cells]. Thus, WASP and the WAVE… (More)

Macroautophagy (hereafter autophagy) is the process by which cytosolic material destined for degradation is enclosed inside a… (More)

RhoD is a member of the Rho GTPase family and it coordinates actin dynamics and membrane trafficking. Activation of RhoD results… (More)

Junction-mediating and regulatory protein (JMY) was originally identified as a transcriptional co-factor in the p53-response to… (More)

The microtubule (MT) and actin cytoskeletons drive many essential cellular processes, yet fairly little is known about how their… (More)

T he protein WHAMM serves as an intermediary between the microtubule and actin cytoskeletons. Shen et al. discover that binding… (More)

WASP family proteins stimulate the actin-nucleating activity of the ARP2/3 complex. They include members of the well-known WASP… (More)

Arp2/3 complex mediates the nucleation of actin filaments in multiple subcellular processes, and is activated by nucleation… (More)

The Arp2/3 complex is an actin nucleator that plays a critical role in many cellular processes. Its activities are regulated by… (More)