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WDR83 gene

Known as: MAPK organizer 1, WD repeat domain 83, WDR83 
 
National Institutes of Health

Papers overview

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2015
2015
Morg1 heterozygous deficiency ameliorates hypoxia-induced acute renal injury.
Acute kidney injury is a common complication of critically ill patients and may occur as a result of various factors and… Expand
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2014
2014
Targeted extracellular signal-regulated kinase activation mediated by Leishmania amazonensis requires MP1 scaffold.
Leishmania amazonensis infection promotes alteration of host cellular signaling and intracellular parasite survival, but specific… Expand
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2013
2013
Advanced glycated end-products affect HIF-transcriptional activity in renal cells.
Advanced glycated end-products (AGEs) are ligands of the receptor for AGEs and increase in diabetic disease. MAPK organizer 1… Expand
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2013
2013
The WD40 protein Morg1 facilitates Par6–aPKC binding to Crb3 for apical identity in epithelial cells
Par6–aPKC recruitment to the premature apical membrane through Morg1 interaction with Par6 is required for definition of apical… Expand
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2013
2013
SNPs detection in DHPS-WDR83 overlapping genes mapping on porcine chromosome 2 in a QTL region for meat pH
BackgroundThe pH is an important parameter influencing technological quality of pig meat, a trait affected by environmental and… Expand
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2012
2012
Bidirectional regulation between WDR83 and its natural antisense transcript DHPS in gastric cancer
Natural antisense transcripts (NATs) exist ubiquitously in mammalian genomes and play roles in the regulation of gene expression… Expand
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2012
2012
Morg1+/− heterozygous mice are protected from experimentally induced focal cerebral ischemia
Focal cerebral ischemia (stroke) and reperfusion injury leads to acute and chronic brain damage. The increase of the hypoxia… Expand
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2009
2009
Morg1 heterozygous mice are protected from acute renal ischemia-reperfusion injury.
Renal ischemia and reperfusion injury leads to acute renal failure when proinflammatory and apoptotic processes in the kidney are… Expand
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Highly Cited
2006
Highly Cited
2006
The Novel WD-repeat Protein Morg1 Acts as a Molecular Scaffold for Hypoxia-inducible Factor Prolyl Hydroxylase 3 (PHD3)*
Hypoxia-inducible factor-1 (HIF-1), a transcriptional complex composed of an oxygen-sensitive α- and a β-subunit, plays a pivotal… Expand
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Highly Cited
2004
Highly Cited
2004
Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists.
Signal transduction occurs by the reversible assembly of oligomeric protein complexes that include both enzymatic proteins and… Expand
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