WAY-362450

Known as: FXR-450, XL335 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2014
02420092014

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
INTRODUCTION Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific disorder, which is characterized by raised serum… (More)
Is this relevant?
2014
2014
Alcoholic liver disease (ALD) is a common cause of advanced liver disease, and considered as a major risk factor of morbidity and… (More)
Is this relevant?
2014
2014
Fructose is a key dietary factor in the development of nonalcoholic fatty liver disease (NAFLD). Here we investigated whether WAY… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2012
2012
Farnesoid X receptor (FXR), a bile acid-activated nuclear hormone receptor, plays an important role in the regulation of… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2010
2010
In an effort to develop orally active farnesoid X receptor (FXR) agonists, a series of tetrahydroazepinoindoles with appended… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
BACKGROUND/AIMS The farnesoid X receptor (FXR) is a member of the nuclear hormone receptor superfamily, which plays an essential… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
Azepino[4,5-b]indoles have been identified as potent agonists of the farnesoid X receptor (FXR). In vitro and in vivo… (More)
Is this relevant?
2009
2009
The role of farnesoid X receptor (FXR) in the development of atherosclerosis has been unclear. Here, LDL receptor (LDLR(-/-)) or… (More)
Is this relevant?
2009
2009
C-reactive protein (CRP), a human acute-phase protein, is a risk factor for future cardiovascular events and exerts direct pro… (More)
Is this relevant?
2009
2009
The nuclear hormone receptor farnesoid X receptor (FXR) plays a critical role in the regulation of bile acid, triglyceride (TG… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?