WASH complex

Known as: WASH complex location 
A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In… (More)

Topic mentions per year

Topic mentions per year

2009-2017
0246820092017

Papers overview

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Highly Cited
2014
Highly Cited
2014
Endosomal protein sorting controls the localization of many physiologically important proteins and is linked to several… (More)
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2014
2014
Retromer is a protein assembly that plays a central role in orchestrating export of transmembrane-spanning cargo proteins from… (More)
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2014
2014
Retromer is a vital element of the endosomal protein sorting machinery and comprises two subcomplexes that operate together to… (More)
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2013
2013
BACKGROUND INFORMATION The Wiskott-Aldrich syndrome protein and scar homolog (WASH) complex is the major Arp2/3 activator at the… (More)
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2013
2013
WASH causes actin to polymerize on vesicles involved in retrograde traffic and exocytosis. It is found within a regulatory… (More)
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2013
2013
Vesicle biogenesis machinery components such as coat proteins can interact with the actin cytoskeleton for cargo sorting into… (More)
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2013
2013
Mutations in the gene encoding strumpellin cause autosomal dominant hereditary spastic paraplegia (HSP), in which there is… (More)
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Highly Cited
2012
Highly Cited
2012
The retromer complex is a conserved endosomal protein sorting complex that sorts membrane proteins into nascent endosomal tubules… (More)
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2011
2011
High-throughput sequencing has greatly facilitated the elucidation of genetic disorders, but compared with X-linked and autosomal… (More)
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Highly Cited
2009
Highly Cited
2009
The Arp2/3 complex regulates endocytosis, sorting, and trafficking, yet the Arp2/3-stimulating factors orchestrating these… (More)
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