Velcade
National Institutes of Health
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Innovation has frequently been described as the key to drug discovery. However, in the daily routine, medicinal chemists often…
Purpose: Bortezomib (Velcade), a dipeptide boronate 20S proteasome inhibitor and an approved treatment option for multiple…
Multiple myeloma is an incurable plasma cell neoplasia characterized by the production of large amounts of monoclonal…
The dipeptide boronic acid analogue VELCADE™ (Bortezomib; formerly known as PS-341, LDP-341 and MLM341) is a potent and selective…
Melanoma poses a great challenge to patients, oncologists, and biologists because of its nearly universal resistance to…