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VU590

 
National Institutes of Health

Papers overview

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2017
2017
VU590 was the first publicly disclosed, submicromolar-affinity (IC50 = 0.2 μM), small-molecule inhibitor of the inward rectifier… Expand
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2017
2017
KIR7.1, an inwardly rectifying K+ channel, plays a critical role in regulating uterine excitability during pregnancy and has been… Expand
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2017
2017
The KCNJ13 gene encodes the inwardly rectifying potassium channel, Kir7.1. Mutations in this gene cause childhood blindness, in… Expand
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2015
2015
Malpighian tubules of adult female yellow fever mosquitoes Aedes aegypti express three inward rectifier K(+) (Kir) channel… Expand
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2015
2015
Kir7.1 is an inwardly rectifying potassium channel that has been implicated in controlling the resting membrane potential of the… Expand
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2014
2014
Abnormal uterine activity in pregnancy causes a range of important clinical disorders, including preterm birth, dysfunctional… Expand
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2014
2014
Mosquitoes are important disease vectors that transmit a wide variety of pathogens to humans, including those that cause malaria… Expand
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2011
2011
The renal outer medullary potassium (K+) channel, ROMK (Kir1.1), is a putative drug target for a novel class of loop diuretic… Expand
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2009
2009
The renal outer medullary potassium channel (ROMK) is expressed in the kidney tubule and critically regulates sodium and… Expand
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2009
2009
The renal outer medullary potassium channel (ROMK) is expressed in the kidney tubule and critically regulates sodium and… Expand
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